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10.1155/2014/273473 http://scihub22266oqcxt.onion/10.1155/2014/273473 C4052151!4052151!24949430     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomed+Res+Int 2014 ; 2014 (ä): ä Nephropedia Template TP {{tp|p=24949430|t=2014. Autophagy in Drosophila: From Historical Studies to Current Knowledge |pdf=|usr=}}{{24949430}} gab.com Text Autophagy in Drosophila: From Historical Studies to Current Knowledge JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=24949430 #FOAvip The discovery of evolutionarily conserved Atg genes required for autophagy in yeast truly revolutionized this research field and made it possible to carry out functional studies on model organisms. Insects including Drosophila are classical and still popular models to study autophagy, starting from the 1960s. This review aims to summarize past achievements and our current knowledge about the role and regulation of autophagy in Drosophila, with an outlook to yeast and mammals. The basic mechanisms of autophagy in fruit fly cells appear to be quite similar to other eukaryotes, and the role that this lysosomal self-degradation process plays in Drosophila models of various diseases already made it possible to recognize certain aspects of human pathologies. Future studies in this complete animal hold great promise for the better understanding of such processes and may also help finding new research avenues for the treatment of disorders with misregulated autophagy. Twit Text FOAVip Autophagy in Drosophila: From Historical Studies to Current Knowledge ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=24949430 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24949430 #FOAvip English Wikipedia <ref>{{Cite pmid|24949430}}</ref> Autophagy in Drosophila: From Historical Studies to Current Knowledge #MMPMID24949430 Mulakkal NC; Nagy P; Takats S; Tusco R; Juhász G; Nezis IP Biomed Res Int 2014[]; 2014 (ä): ä PMID24949430show ga The discovery of evolutionarily conserved Atg genes required for autophagy in yeast truly revolutionized this research field and made it possible to carry out functional studies on model organisms. Insects including Drosophila are classical and still popular models to study autophagy, starting from the 1960s. This review aims to summarize past achievements and our current knowledge about the role and regulation of autophagy in Drosophila, with an outlook to yeast and mammals. The basic mechanisms of autophagy in fruit fly cells appear to be quite similar to other eukaryotes, and the role that this lysosomal self-degradation process plays in Drosophila models of various diseases already made it possible to recognize certain aspects of human pathologies. Future studies in this complete animal hold great promise for the better understanding of such processes and may also help finding new research avenues for the treatment of disorders with misregulated autophagy. äAutophagy in Drosophila: From Historical Studies to Current Knowledge (epmc).pdf DeepDyve Pubget Overpricing