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10.1007/978-1-4614-0254-1_13 http://scihub22266oqcxt.onion/10.1007/978-1-4614-0254-1_13 C4049144!4049144!21901626     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\21901626.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Adv+Exp+Med+Biol 2011 ; 720 (ä): 163-70 Nephropedia Template TP {{tp|p=21901626|t=2011. Mechanism of Radiation Carcinogenesis: Role of theTGFBI Gene and the Inflammatory Signaling Cascade |pdf=|usr=}}{{21901626}} gab.com Text Mechanism of Radiation Carcinogenesis: Role of theTGFBI Gene and the Inflammatory Signaling Cascade JO: Adv Exp Med Biol http://www.kidney.de/pget.php?&tw=1&pmid=21901626 #FOAvip Using an immortalized human bronchial epithelial cell line, we showed previously that the transforming growth factor beta-induced (TGFBI) gene was consistently downregulated by six- to sevenfold among radiation-induced tumorigenic human cells when compared with controls. Trans- fection of TGFBI gene into tumor cells resulted in a significant reduction in tumor growth as well as in vitro anchorage independent growth. The observations that TGFBI knock-out animals showed increased spontaneous tumor incidence and chemically induced tumors highlight the suppressive nature of the gene. There is evidence that extranuclear/extracellular targets are important in low-dose radiation response and that the cyclo-oxygenase-2 signaling pathway mediates the process. The involvement of NF?B-dependent cytokines and the resultant inflammatory response works in concert with in modulating radiation-induced bronchial carcinogenesis. Twit Text FOAVip Mechanism of Radiation Carcinogenesis: Role of theTGFBI Gene and the Inflammatory Signaling Cascade ????Adv Exp Med Biol http://www.kidney.de/pget.php?&tw=1&pmid=21901626 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21901626 #FOAvip English Wikipedia <ref>{{Cite pmid|21901626}}</ref> Mechanism of Radiation Carcinogenesis: Role of theTGFBI Gene and the Inflammatory Signaling Cascade #MMPMID21901626 Hei TK; Zhao Y; Zhou H; Ivanov V Adv Exp Med Biol 2011[]; 720 (ä): 163-70 PMID21901626show ga Using an immortalized human bronchial epithelial cell line, we showed previously that the transforming growth factor beta-induced (TGFBI) gene was consistently downregulated by six- to sevenfold among radiation-induced tumorigenic human cells when compared with controls. Trans- fection of TGFBI gene into tumor cells resulted in a significant reduction in tumor growth as well as in vitro anchorage independent growth. The observations that TGFBI knock-out animals showed increased spontaneous tumor incidence and chemically induced tumors highlight the suppressive nature of the gene. There is evidence that extranuclear/extracellular targets are important in low-dose radiation response and that the cyclo-oxygenase-2 signaling pathway mediates the process. The involvement of NF?B-dependent cytokines and the resultant inflammatory response works in concert with in modulating radiation-induced bronchial carcinogenesis. äMechanism of Radiation Carcinogenesis: Role of theTGFBI Gene and the I(epmc).pdf DeepDyve Pubget Overpricing