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2014 ; 90
(6
): 988-92
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Maripa hantavirus in French Guiana: phylogenetic position and predicted spatial
distribution of rodent hosts
#MMPMID24752689
de Thoisy B
; Matheus S
; Catzeflis F
; Clément L
; Barrioz S
; Guidez A
; Donato D
; Cornu JF
; Brunaux O
; Guitet S
; Lacoste V
; Lavergne A
Am J Trop Med Hyg
2014[Jun]; 90
(6
): 988-92
PMID24752689
show ga
A molecular screening of wild-caught rodents was conducted in French Guiana,
South America to identify hosts of the hantavirus Maripa described in 2008 in a
hantavirus pulmonary syndrome (HPS) case. Over a 9-year period, 418 echimyids and
murids were captured. Viral RNA was detected in two sigmodontine rodents,
Oligoryzomys fulvescens and Zygodontomys brevicauda, trapped close to the house
of a second HPS case that occurred in 2009 and an O. fulvescens close to the
fourth HPS case identified in 2013. Sequences from the rodents had 96% and 97%
nucleotide identity (fragment of S and M segments, respectively) with the
sequence of the first human HPS case. Phylogenetic reconstructions based on the
complete sequence of the S segment show that Maripa virus is closely related to
Rio Mamore hantavirus. Using environmental descriptors of trapping sites,
including vegetation, landscape units, rain, and human disturbance, a maximal
entropy-based species distribution model allowed for identification of areas of
higher predicted occurrence of the two rodents, where emergence risks of Maripa
virus are expected to be higher.