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10.1074/jbc.M114.560359

http://scihub22266oqcxt.onion/10.1074/jbc.M114.560359
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C4047404!4047404!24759100
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suck abstract from ncbi


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pmid24759100      J+Biol+Chem 2014 ; 289 (23): 16362-73
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  • Critical Role for NAD Glycohydrolase in Regulation of Erythropoiesis by Hematopoietic Stem Cells through Control of Intracellular NAD Content* #MMPMID24759100
  • Nam TS; Park KH; Shawl AI; Kim BJ; Han MK; Kim Y; Moss J; Kim UH
  • J Biol Chem 2014[Jun]; 289 (23): 16362-73 PMID24759100show ga
  • Background: The structure and function of NAD glycohydrolases (NADases) with pure hydrolytic activity are unclear.Results: We show that a novel NADase, exclusively expressed in rabbit reticulocytes, affects erythropoiesis.Conclusion: The intracellular NAD level regulated by the NADase is critical for erythropoiesis.Significance: We show that NADase activity regulates erythropoiesis of hematopoietic stem cells.
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