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10.1074/jbc.M114.564252 http://scihub22266oqcxt.onion/10.1074/jbc.M114.564252 C4047371!4047371!24755219     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2014 ; 289 (23): 15969-78 Nephropedia Template TP {{tp|p=24755219|t=2014. Galiellalactone Is a Direct Inhibitor of the Transcription Factor STAT3 in Prostate Cancer Cells*? |pdf=|usr=}}{{24755219}} gab.com Text Galiellalactone Is a Direct Inhibitor of the Transcription Factor STAT3 in Prostate Cancer Cells* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24755219 #FOAvip Background: STAT3 is constitutively active in castration-resistant prostate cancer and the fungal metabolite galiellalactone inhibits STAT3 signaling.Results: Galiellalactone binds covalently to one or more cysteines in STAT3 and prevents STAT3 binding to DNA.Conclusion: Galiellalactone inhibits STAT3 signaling by binding directly to STAT3.Significance: Galiellalactone is a promising direct STAT3 inhibitor for treatment of castration-resistant prostate cancer. Twit Text FOAVip Galiellalactone Is a Direct Inhibitor of the Transcription Factor STAT3 in Prostate Cancer Cells* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24755219 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24755219 #FOAvip English Wikipedia <ref>{{Cite pmid|24755219}}</ref> Galiellalactone Is a Direct Inhibitor of the Transcription Factor STAT3 in Prostate Cancer Cells*? #MMPMID24755219 Don-Doncow N; Escobar Z; Johansson M; Kjellström S; Garcia V; Munoz E; Sterner O; Bjartell A; Hellsten R J Biol Chem 2014[Jun]; 289 (23): 15969-78 PMID24755219show ga Background: STAT3 is constitutively active in castration-resistant prostate cancer and the fungal metabolite galiellalactone inhibits STAT3 signaling.Results: Galiellalactone binds covalently to one or more cysteines in STAT3 and prevents STAT3 binding to DNA.Conclusion: Galiellalactone inhibits STAT3 signaling by binding directly to STAT3.Significance: Galiellalactone is a promising direct STAT3 inhibitor for treatment of castration-resistant prostate cancer. äGaliellalactone Is a Direct Inhibitor of the Transcription Factor STAT(epmc).pdf DeepDyve Pubget Overpricing