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10.1016/j.actbio.2014.04.001 http://scihub22266oqcxt.onion/10.1016/j.actbio.2014.04.001 C4041819!4041819!24726956     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Biomater 2014 ; 10 (7): 2945-55 Nephropedia Template TP {{tp|p=24726956|t=2014. Development of optical probes for in vivo imaging of polarized macrophages during foreign body reactions |pdf=|usr=}}{{24726956}} gab.com Text Development of optical probes for in vivo imaging of polarized macrophages during foreign body reactions JO: Acta Biomater http://www.kidney.de/pget.php?&tw=1&pmid=24726956 #FOAvip Plasticity of macrophages (M?) phenotypes exist in a spectrum from classically activated (M1) cells, to alternatively activated (M2) cells, contributing to both the normal healing of tissues and the pathogenesis of implant failure. Here, folate- and mannose-based optical probes were fabricated to simultaneously determine the degree of M? polarization. In vitro tests show the ability of these probes to specifically target M1 and M2 cells. In an in vivo murine model, they were able to distinguish between M1-dominated inflammatory response to infection and M2-dominated regenerative response to particle implants. Finally, the probes were used to assess the inflammatory/ regenerative property of biomaterial implants. Our results show that these probes can be used to monitor and quantify the dynamic processes of M? polarization and their role in cellular responses in real time. Twit Text FOAVip Development of optical probes for in vivo imaging of polarized macrophages during foreign body reactions ????Acta Biomater http://www.kidney.de/pget.php?&tw=1&pmid=24726956 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24726956 #FOAvip English Wikipedia <ref>{{Cite pmid|24726956}}</ref> Development of optical probes for in vivo imaging of polarized macrophages during foreign body reactions #MMPMID24726956 Baker DW; Zhou J; Tsai YT; Patty KM; Weng H; Tang EN; Nair A; Hu WJ; Tang L Acta Biomater 2014[Jul]; 10 (7): 2945-55 PMID24726956show ga Plasticity of macrophages (M?) phenotypes exist in a spectrum from classically activated (M1) cells, to alternatively activated (M2) cells, contributing to both the normal healing of tissues and the pathogenesis of implant failure. Here, folate- and mannose-based optical probes were fabricated to simultaneously determine the degree of M? polarization. In vitro tests show the ability of these probes to specifically target M1 and M2 cells. In an in vivo murine model, they were able to distinguish between M1-dominated inflammatory response to infection and M2-dominated regenerative response to particle implants. Finally, the probes were used to assess the inflammatory/ regenerative property of biomaterial implants. Our results show that these probes can be used to monitor and quantify the dynamic processes of M? polarization and their role in cellular responses in real time. äDevelopment of optical probes for in vivo imaging of polarized macroph(epmc).pdf DeepDyve Pubget Overpricing