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Renal angiomyolipoma: a radiological classification and update on recent
developments in diagnosis and management
#MMPMID24504542
Jinzaki M
; Silverman SG
; Akita H
; Nagashima Y
; Mikami S
; Oya M
Abdom Imaging
2014[Jun]; 39
(3
): 588-604
PMID24504542
show ga
Angiomyolipoma is the most common benign solid renal neoplasm observed in
clinical practice. Once thought to be a hamartoma and almost always diagnosed by
the imaged-based detection of fat, angiomyolipomas are now known to consist of a
heterogeneous group of neoplasms. Although all are considered perivascular
epithelioid cell tumors, many display different pathology, imaging features, and
clinical behavior. The importance of understanding this group of neoplasms is
emphasized by the fact that many types of angiomyolipoma contain little to no
fat, and despite being benign, sometimes escape a pre-operative diagnosis. These
types of angiomyolipomas can all be considered when encountering a renal mass
that is both hyperattenuating relative to renal parenchyma on unenhanced CT and
T2-hypointense, features that reflect their predominant smooth muscle component.
We review recent developments and provide a radiological classification of
angiomyolipomas that helps physicians understand the various types and learn how
to both diagnose and manage them.