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10.1242/jcs.139923 http://scihub22266oqcxt.onion/10.1242/jcs.139923 C4038943!4038943!24706948     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cell+Sci 2014 ; 127 (11): 2483-92 Nephropedia Template TP {{tp|p=24706948|t=2014. Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation |pdf=|usr=}}{{24706948}} gab.com Text Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation JO: J Cell Sci http://www.kidney.de/pget.php?&tw=1&pmid=24706948 #FOAvip By definition, all epithelial cells have apical?basal polarity, but it is unclear how epithelial polarity is acquired and how polarized cells engage in tube formation. Here, we show that hepatocyte polarization is linked to cytokinesis using the rat hepatocyte cell line Can 10. Before abscission, polarity markers are delivered to the site of cell division in a strict spatiotemporal order. Immediately after abscission, daughter cells remain attached through a unique disc-shaped structure, which becomes the site for targeted exocytosis, resulting in the formation of a primitive bile canaliculus. Subsequently, oriented cell division and asymmetric cytokinesis occur at the bile canaliculus midpoint, resulting in its equal partitioning into daughter cells. Finally, successive cycles of oriented cell division and asymmetric cytokinesis lead to the formation of a tubular bile canaliculus, which is shared by two rows of hepatocytes. These findings define a novel mechanism for cytokinesis-linked polarization and tube formation, which appears to be broadly conserved in diverse cell types. Twit Text FOAVip Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation ????J Cell Sci http://www.kidney.de/pget.php?&tw=1&pmid=24706948 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24706948 #FOAvip English Wikipedia <ref>{{Cite pmid|24706948}}</ref> Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation #MMPMID24706948 Wang T; Yanger K; Stanger BZ; Cassio D; Bi E J Cell Sci 2014[Jun]; 127 (11): 2483-92 PMID24706948show ga By definition, all epithelial cells have apical?basal polarity, but it is unclear how epithelial polarity is acquired and how polarized cells engage in tube formation. Here, we show that hepatocyte polarization is linked to cytokinesis using the rat hepatocyte cell line Can 10. Before abscission, polarity markers are delivered to the site of cell division in a strict spatiotemporal order. Immediately after abscission, daughter cells remain attached through a unique disc-shaped structure, which becomes the site for targeted exocytosis, resulting in the formation of a primitive bile canaliculus. Subsequently, oriented cell division and asymmetric cytokinesis occur at the bile canaliculus midpoint, resulting in its equal partitioning into daughter cells. Finally, successive cycles of oriented cell division and asymmetric cytokinesis lead to the formation of a tubular bile canaliculus, which is shared by two rows of hepatocytes. These findings define a novel mechanism for cytokinesis-linked polarization and tube formation, which appears to be broadly conserved in diverse cell types. äCytokinesis defines a spatial landmark for hepatocyte polarization and(epmc).pdf DeepDyve Pubget Overpricing