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10.1155/2014/971857 http://scihub22266oqcxt.onion/10.1155/2014/971857 C4037588!4037588 !24901003     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24901003 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Biomed+Res+Int 2014 ; 2014 (ä): 971857 Nephropedia Template TP {{tp|p=24901003 |t=2014. O18Quant: a semiautomatic strategy for quantitative analysis of high-resolution 16O/18O labeled data |pdf=|usr=}}{{24901003 }} gab.com Text O18Quant: a semiautomatic strategy for quantitative analysis of high-resolution 16O/18O labeled data JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=24901003 #FOAvip Proteolytic (18)O-labeling has been widely used in quantitative proteomics since it can uniformly label all peptides from different kinds of proteins. There have been multiple algorithms and tools developed over the last few years to analyze high-resolution proteolytic (16)O/(18)O labeled mass spectra. We have developed a software package, O18Quant, which addresses two major issues in the previously developed algorithms. First, O18Quant uses a robust linear model (RLM) for peptide-to-protein ratio estimation. RLM can minimize the effect of outliers instead of iteratively removing them which is a common practice in other approaches. Second, the existing algorithms lack applicable implementation. We address this by implementing O18Quant using C# under Microsoft.net framework and R. O18Quant automatically calculates the peptide/protein relative ratio and provides a friendly graphical user interface (GUI) which allows the user to manually validate the quantification results at scan, peptide, and protein levels. The intuitive GUI of O18Quant can greatly enhance the user's visualization and understanding of the data analysis. O18Quant can be downloaded for free as part of the software suite ProteomicsTools. Twit Text FOAVip O18Quant: a semiautomatic strategy for quantitative analysis of high-resolution 16O/18O labeled data ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=24901003 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24901003 #FOAvip English Wikipedia <ref>{{Cite pmid|24901003 }}</ref> O18Quant: a semiautomatic strategy for quantitative analysis of high-resolution 16O/18O labeled data #MMPMID24901003 Guo Y ; Miyagi M ; Zeng R ; Sheng Q Biomed Res Int 2014[]; 2014 (ä): 971857 PMID24901003 show ga Proteolytic (18)O-labeling has been widely used in quantitative proteomics since it can uniformly label all peptides from different kinds of proteins. There have been multiple algorithms and tools developed over the last few years to analyze high-resolution proteolytic (16)O/(18)O labeled mass spectra. We have developed a software package, O18Quant, which addresses two major issues in the previously developed algorithms. First, O18Quant uses a robust linear model (RLM) for peptide-to-protein ratio estimation. RLM can minimize the effect of outliers instead of iteratively removing them which is a common practice in other approaches. Second, the existing algorithms lack applicable implementation. We address this by implementing O18Quant using C# under Microsoft.net framework and R. O18Quant automatically calculates the peptide/protein relative ratio and provides a friendly graphical user interface (GUI) which allows the user to manually validate the quantification results at scan, peptide, and protein levels. The intuitive GUI of O18Quant can greatly enhance the user's visualization and understanding of the data analysis. O18Quant can be downloaded for free as part of the software suite ProteomicsTools. |Animals [MESH] |Isotope Labeling/methods [MESH] |Male [MESH] |Mass Spectrometry/methods [MESH] |Oxygen Isotopes/*chemistry [MESH] |Peptides/*chemistry [MESH] |Proteins/*chemistry [MESH] |Proteome/chemistry [MESH] |Proteomics/methods [MESH] |Rats [MESH] |Rats, Sprague-Dawley [MESH] |Retina/chemistry/metabolism [MESH]O18Quant: a semiautomatic strategy for quantitative analysis of high-r(epmc).pdf DeepDyve Pubget Overpricing