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10.1098/rsif.2014.0123 http://scihub22266oqcxt.onion/10.1098/rsif.2014.0123 C4032532!4032532!24759543     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24759543&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+R+Soc+Interface 2014 ; 11 (96): ä Nephropedia Template TP {{tp|p=24759543|t=2014. Is the Donnan effect sufficient to explain swelling in brain tissue slices?|pdf=|usr=}}{{24759543}} gab.com Text Is the Donnan effect sufficient to explain swelling in brain tissue slices JO: J R Soc Interface http://www.kidney.de/pget.php?&tw=1&pmid=24759543 #FOAvip Brain tissue swelling is a dangerous consequence of traumatic injury and is associated with raised intracranial pressure and restricted blood flow. We consider the mechanical effects that drive swelling of brain tissue slices in an ionic solution bath, motivated by recent experimental results that showed that the volume change of tissue slices depends on the ionic concentration of the bathing solution. This result was attributed to the presence of large charged molecules that induce ion concentration gradients to ensure electroneutrality (the Donnan effect), leading to osmotic pressures and water accumulation. We use a mathematical triphasic model for soft tissue to characterize the underlying processes that could lead to the volume changes observed experimentally. We suggest that swelling is caused by an osmotic pressure increase driven by both non-permeating solutes released by necrotic cells, in addition to the Donnan effect. Both effects are necessary to explain the dependence of the tissue slice volume on the ionic bath concentration that was observed experimentally. Twit Text FOAVip Is the Donnan effect sufficient to explain swelling in brain tissue slices ????J R Soc Interface http://www.kidney.de/pget.php?&tw=1&pmid=24759543 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24759543 #FOAvip English Wikipedia <ref>{{Cite pmid|24759543}}</ref> Is the Donnan effect sufficient to explain swelling in brain tissue slices? #MMPMID24759543 Lang GE; Stewart PS; Vella D; Waters SL; Goriely A J R Soc Interface 2014[Jul]; 11 (96): ä PMID24759543show ga Brain tissue swelling is a dangerous consequence of traumatic injury and is associated with raised intracranial pressure and restricted blood flow. We consider the mechanical effects that drive swelling of brain tissue slices in an ionic solution bath, motivated by recent experimental results that showed that the volume change of tissue slices depends on the ionic concentration of the bathing solution. This result was attributed to the presence of large charged molecules that induce ion concentration gradients to ensure electroneutrality (the Donnan effect), leading to osmotic pressures and water accumulation. We use a mathematical triphasic model for soft tissue to characterize the underlying processes that could lead to the volume changes observed experimentally. We suggest that swelling is caused by an osmotic pressure increase driven by both non-permeating solutes released by necrotic cells, in addition to the Donnan effect. Both effects are necessary to explain the dependence of the tissue slice volume on the ionic bath concentration that was observed experimentally. äIs the Donnan effect sufficient to explain swelling in brain tissue sl(epmc).pdf DeepDyve Pubget Overpricing