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10.1093/brain/awt358 http://scihub22266oqcxt.onion/10.1093/brain/awt358 C4032094!4032094 !24477430     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24477430 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Brain 2014 ; 137 (Pt 6 ): 1579-613 Nephropedia Template TP {{tp|p=24477430 |t=2014. Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes |pdf=|usr=}}{{24477430 }} gab.com Text Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes JO: Brain http://www.kidney.de/pget.php?&tw=1&pmid=24477430 #FOAvip The corpus callosum is the largest fibre tract in the brain, connecting the two cerebral hemispheres, and thereby facilitating the integration of motor and sensory information from the two sides of the body as well as influencing higher cognition associated with executive function, social interaction and language. Agenesis of the corpus callosum is a common brain malformation that can occur either in isolation or in association with congenital syndromes. Understanding the causes of this condition will help improve our knowledge of the critical brain developmental mechanisms required for wiring the brain and provide potential avenues for therapies for callosal agenesis or related neurodevelopmental disorders. Improved genetic studies combined with mouse models and neuroimaging have rapidly expanded the diverse collection of copy number variations and single gene mutations associated with callosal agenesis. At the same time, advances in our understanding of the developmental mechanisms involved in corpus callosum formation have provided insights into the possible causes of these disorders. This review provides the first comprehensive classification of the clinical and genetic features of syndromes associated with callosal agenesis, and provides a genetic and developmental framework for the interpretation of future research that will guide the next advances in the field. Twit Text FOAVip Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes ????Brain http://www.kidney.de/pget.php?&tw=1&pmid=24477430 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24477430 #FOAvip English Wikipedia <ref>{{Cite pmid|24477430 }}</ref> Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes #MMPMID24477430 Edwards TJ ; Sherr EH ; Barkovich AJ ; Richards LJ Brain 2014[Jun]; 137 (Pt 6 ): 1579-613 PMID24477430 show ga The corpus callosum is the largest fibre tract in the brain, connecting the two cerebral hemispheres, and thereby facilitating the integration of motor and sensory information from the two sides of the body as well as influencing higher cognition associated with executive function, social interaction and language. Agenesis of the corpus callosum is a common brain malformation that can occur either in isolation or in association with congenital syndromes. Understanding the causes of this condition will help improve our knowledge of the critical brain developmental mechanisms required for wiring the brain and provide potential avenues for therapies for callosal agenesis or related neurodevelopmental disorders. Improved genetic studies combined with mouse models and neuroimaging have rapidly expanded the diverse collection of copy number variations and single gene mutations associated with callosal agenesis. At the same time, advances in our understanding of the developmental mechanisms involved in corpus callosum formation have provided insights into the possible causes of these disorders. This review provides the first comprehensive classification of the clinical and genetic features of syndromes associated with callosal agenesis, and provides a genetic and developmental framework for the interpretation of future research that will guide the next advances in the field. |Agenesis of Corpus Callosum/*genetics/physiopathology [MESH] |Animals [MESH] |Corpus Callosum/*growth & development/pathology [MESH] |Disease Models, Animal [MESH] |Genetic Predisposition to Disease/*genetics [MESH] |Humans [MESH]Clinical, genetic and imaging findings identify new causes for corpus (epmc).pdf DeepDyve Pubget Overpricing