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10.3390/biom2020240 http://scihub22266oqcxt.onion/10.3390/biom2020240 C4030844!4030844!24970135     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomolecules 2012 ; 2 (2): 240-55 Nephropedia Template TP {{tp|p=24970135|t=2012. The Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer |pdf=|usr=}}{{24970135}} gab.com Text The Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer JO: Biomolecules http://www.kidney.de/pget.php?&tw=1&pmid=24970135 #FOAvip SUMO (small ubiquitin-related modifier) conjugation is a reversible three-step process of protein post-translational modifications mediating protein-protein interactions, subcellular compartmentalization and regulation of transcriptional events. Among divergent transcription factors regulated by SUMOylation and deSUMOylation, the androgen receptor (AR) is of exceptional significance, given its established role in prostate carcinogenesis. The enzymes of the SUMO pathway can have diverse effects on AR transcriptional activity, either via direct modification of the AR or through modification of AR co-regulators. Accumulating in vitro and in vivo evidence implicates the SUMO pathway in AR-dependent signaling. Prostate cancer cell proliferation and hypoxia-induced angiogenesis are also regulated by the SUMO pathway, through an AR-independent mechanism. Thus, an important role has been revealed for members of the SUMO pathway in prostate cancer (PCa) development and progression, offering new therapeutic targets. Twit Text FOAVip The Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer ????Biomolecules http://www.kidney.de/pget.php?&tw=1&pmid=24970135 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24970135 #FOAvip English Wikipedia <ref>{{Cite pmid|24970135}}</ref> The Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer #MMPMID24970135 Vlachostergios PJ; Papandreou CN Biomolecules 2012[Jun]; 2 (2): 240-55 PMID24970135show ga SUMO (small ubiquitin-related modifier) conjugation is a reversible three-step process of protein post-translational modifications mediating protein-protein interactions, subcellular compartmentalization and regulation of transcriptional events. Among divergent transcription factors regulated by SUMOylation and deSUMOylation, the androgen receptor (AR) is of exceptional significance, given its established role in prostate carcinogenesis. The enzymes of the SUMO pathway can have diverse effects on AR transcriptional activity, either via direct modification of the AR or through modification of AR co-regulators. Accumulating in vitro and in vivo evidence implicates the SUMO pathway in AR-dependent signaling. Prostate cancer cell proliferation and hypoxia-induced angiogenesis are also regulated by the SUMO pathway, through an AR-independent mechanism. Thus, an important role has been revealed for members of the SUMO pathway in prostate cancer (PCa) development and progression, offering new therapeutic targets. äThe Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Pro(epmc).pdf DeepDyve Pubget Overpricing