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2014 ; 16
(4
): e15603
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Design and construct an optical device to determine relative blood volume in
patients undergoing hemodialysis
#MMPMID24910804
Dormanesh B
; Tofangchiha S
; Abouei V
; Sharifian H
Iran Red Crescent Med J
2014[Apr]; 16
(4
): e15603
PMID24910804
show ga
BACKGROUND: Occurrence of hypotension during hemodialysis in nearly 20-30% of
patients, shows is the necessity of continuous monitoring the patients' blood
pressure during hemodialysis. Since directly and non-invasively continuous blood
pressure monitoring, is not easy, finding a parameter related to blood pressure,
for indirect monitoring is of great value. Related blood volume (RBV) is one of
the parameters, related to blood pressure and have a good potential to reflect
the patient's hemodynamic condition. OBJECTIVES: The main objective of this study
was to design and construct an optical device to determine the RBV in patients
undergoing hemodialysis, during the process. MATERIALS AND METHODS: After initial
studies in order to select a proper sensor, using the ORCAD software, an analog
circuit was designed. The implementation and modification of the circuit was done
by the clinical tests, using expired blood. Afterwards, for calculation the RBV,
controlling the display, data storage and sending it to the computer, an ATmega16
microcontroller was used. For programing the microcontroller, CodeVision software
and then Altium Designer software were used for the circuit compression, in order
to design the printed circuit board. Finally, all parts of the analog and digital
circuit, AC to DC converter and the LCD were embedded in a box. RESULTS: After
finalization of the device and before testing it in a real situation, expired
blood was used for final evaluation. The evaluation was done by changing the
blood concentration, at the start point by adding water to it. In fact, the
device can track the changes in blood concentration and display the RBV. After
this evaluation, the device was tested in a clinical situation. The results
showed there are no interactions between this device and the other devices used
in the dialysis section and it can work properly in order to measure the RBV.
CONCLUSIONS: Considering the hypotension and its consequences in a patient on
hemodialysis, solving this problem seems necessary. One method for preventing
this, is to use the blood pressure related parameters and one of these parameters
is the RBV. In this study, in order to measure the RBV, a device was designed and
evaluated by expired blood and also tested in a clinical situation. Results
showed that the device could work properly in order to measure the RBV.