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10.1021/ml200259q http://scihub22266oqcxt.onion/10.1021/ml200259q C4025662!4025662!24900437     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ACS+Med+Chem+Lett 2012 ; 3 (2): 135-9 Nephropedia Template TP {{tp|p=24900437|t=2012. Discovery of CX-6258 A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor |pdf=|usr=}}{{24900437}} gab.com Text Discovery of CX-6258 A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor JO: ACS Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=24900437 #FOAvip Structure?activity relationship analysis in a series of 3-(5-((2-oxoindolin-3-ylidene)methyl)furan-2-yl)amides identified compound 13, a pan-Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. Compound 13 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models. Twit Text FOAVip Discovery of CX-6258 A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor ????ACS Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=24900437 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24900437 #FOAvip English Wikipedia <ref>{{Cite pmid|24900437}}</ref> Discovery of CX-6258 A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor #MMPMID24900437 Haddach M; Michaux J; Schwaebe MK; Pierre F; O?Brien SE; Borsan C; Tran J; Raffaele N; Ravula S; Drygin D; Siddiqui-Jain A; Darjania L; Stansfield R; Proffitt C; Macalino D; Streiner N; Bliesath J; Omori M; Whitten JP; Anderes K; Rice WG; Ryckman D ACS Med Chem Lett 2012[Feb]; 3 (2): 135-9 PMID24900437show ga Structure?activity relationship analysis in a series of 3-(5-((2-oxoindolin-3-ylidene)methyl)furan-2-yl)amides identified compound 13, a pan-Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. Compound 13 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models. äDiscovery of CX-6258 A Potent, Selective, and Orally Efficacious pan-(epmc).pdf DeepDyve Pubget Overpricing