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10.1016/j.tibs.2014.02.003 http://scihub22266oqcxt.onion/10.1016/j.tibs.2014.02.003 C4021867!4021867!24630600     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Biochem+Sci 2014 ; 39 (4): 159-69 Nephropedia Template TP {{tp|p=24630600|t=2014. FOXO transcription factors: key regulators of cellular quality control |pdf=|usr=}}{{24630600}} gab.com Text FOXO transcription factors: key regulators of cellular quality control JO: Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=24630600 #FOAvip FOXO transcription factors are conserved regulators of longevity downstream of insulin signaling. These transcription factors integrate signals emanating from nutrient deprivation and stress stimuli to coordinate programs of genes involved in cellular metabolism and resistance to oxidative stress. Here we discuss emerging evidence for a pivotal role of FOXO factors in promoting the expression of genes involved in autophagy and the ubiquitin-proteasome system ? two cell clearance processes that are essential for maintaining organelle and protein homeostasis (proteostasis). The ability of FOXO to maintain cellular quality control appears to be critical in processes and pathologies where damaged proteins and organelles accumulate, including aging and neurodegenerative diseases. Twit Text FOAVip FOXO transcription factors: key regulators of cellular quality control ????Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=24630600 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24630600 #FOAvip English Wikipedia <ref>{{Cite pmid|24630600}}</ref> FOXO transcription factors: key regulators of cellular quality control #MMPMID24630600 Webb AE; Brunet A Trends Biochem Sci 2014[Apr]; 39 (4): 159-69 PMID24630600show ga FOXO transcription factors are conserved regulators of longevity downstream of insulin signaling. These transcription factors integrate signals emanating from nutrient deprivation and stress stimuli to coordinate programs of genes involved in cellular metabolism and resistance to oxidative stress. Here we discuss emerging evidence for a pivotal role of FOXO factors in promoting the expression of genes involved in autophagy and the ubiquitin-proteasome system ? two cell clearance processes that are essential for maintaining organelle and protein homeostasis (proteostasis). The ability of FOXO to maintain cellular quality control appears to be critical in processes and pathologies where damaged proteins and organelles accumulate, including aging and neurodegenerative diseases. äFOXO transcription factors: key regulators of cellular quality control(epmc).pdf DeepDyve Pubget Overpricing