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10.1016/j.gtc.2014.02.004 http://scihub22266oqcxt.onion/10.1016/j.gtc.2014.02.004 C4019936!4019936!24813513     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Gastroenterol+Clin+North+Am 2014 ; 43 (2): 243-56 Nephropedia Template TP {{tp|p=24813513|t=2014. Eosinophilic Esophagitis: Interactions with Gastroesophageal Reflux Disease |pdf=|usr=}}{{24813513}} gab.com Text Eosinophilic Esophagitis: Interactions with Gastroesophageal Reflux Disease JO: Gastroenterol Clin North Am http://www.kidney.de/pget.php?&tw=1&pmid=24813513 #FOAvip Early authorities on eosinophilic esophagitis (EoE) deemed it crucial to distinguish this disorder from gastroesophageal reflux disease (GERD). However, it has become clear that GERD and EoE are not mutually exclusive disorders, and that their interactions can be complex. The notion that GERD and EoE can be distinguished by the response to PPI treatment is based on the assumption that gastric acid suppression is the only important therapeutic effect of PPIs, and therefore only GERD can respond to PPIs. This assumption appears to be incorrect for two major reasons. First, there are multiple mechanisms whereby PPI-induced acid reduction might benefit patients with EoE. Second, PPIs have acid-independent, anti-inflammatory effects that might be beneficial both for GERD and for EoE. Since the PPIs have multiple effects that might benefit both diseases, for patients who have esophageal symptoms and esophageal eosinophilia, we feel that a clinical and/or histological response to PPIs does not rule in GERD, and does not rule out EoE. However, we do recommend a trial of PPI therapy for patients with symptomatic esophageal eosinophilia, even if the diagnosis of EoE seems clear-cut. Twit Text FOAVip Eosinophilic Esophagitis: Interactions with Gastroesophageal Reflux Disease ????Gastroenterol Clin North Am http://www.kidney.de/pget.php?&tw=1&pmid=24813513 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24813513 #FOAvip English Wikipedia <ref>{{Cite pmid|24813513}}</ref> Eosinophilic Esophagitis: Interactions with Gastroesophageal Reflux Disease #MMPMID24813513 Cheng E; Souza RF; Spechler SJ Gastroenterol Clin North Am 2014[Jun]; 43 (2): 243-56 PMID24813513show ga Early authorities on eosinophilic esophagitis (EoE) deemed it crucial to distinguish this disorder from gastroesophageal reflux disease (GERD). However, it has become clear that GERD and EoE are not mutually exclusive disorders, and that their interactions can be complex. The notion that GERD and EoE can be distinguished by the response to PPI treatment is based on the assumption that gastric acid suppression is the only important therapeutic effect of PPIs, and therefore only GERD can respond to PPIs. This assumption appears to be incorrect for two major reasons. First, there are multiple mechanisms whereby PPI-induced acid reduction might benefit patients with EoE. Second, PPIs have acid-independent, anti-inflammatory effects that might be beneficial both for GERD and for EoE. Since the PPIs have multiple effects that might benefit both diseases, for patients who have esophageal symptoms and esophageal eosinophilia, we feel that a clinical and/or histological response to PPIs does not rule in GERD, and does not rule out EoE. However, we do recommend a trial of PPI therapy for patients with symptomatic esophageal eosinophilia, even if the diagnosis of EoE seems clear-cut. äEosinophilic Esophagitis: Interactions with Gastroesophageal Reflux Di(epmc).pdf DeepDyve Pubget Overpricing