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10.1021/np400947d http://scihub22266oqcxt.onion/10.1021/np400947d C4010298!4010298!24694263     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Nat+Prod 2014 ; 77 (4): 863-72 Nephropedia Template TP {{tp|p=24694263|t=2014. Antineoplastic Agents 595 Structural Modifications of Betulin and the X-ray Crystal Structure of an Unusual Betulin Amine Dimer1 |pdf=|usr=}}{{24694263}} gab.com Text Antineoplastic Agents 595 Structural Modifications of Betulin and the X-ray Crystal Structure of an Unusual Betulin Amine Dimer1 JO: J Nat Prod http://www.kidney.de/pget.php?&tw=1&pmid=24694263 #FOAvip The lupane-type triterpene betulin (1) has been subjected to a series of structural modifications for the purpose of evaluating resultant cancer cell growth inhibitory activity. The reaction sequence 7 ? 11 ? 12 was especially noteworthy in providing a betulin-derived amine dimer. Other unexpected synthetic results included the 11 and 13/14 ? 17 conversions, which yielded an imidazo derivative. X-ray crystal structures of dimer 12 and intermediate 25 are reported. All of the betulin modifications were examined for anticancer activity against the P388 murine and human cell lines. Significant cancer cell growth inhibition was found for 4, 8, 9, 15/16, 19, 20, 24, and 26, which further defines the utility of the betulin scaffold. Twit Text FOAVip Antineoplastic Agents 595 Structural Modifications of Betulin and the X-ray Crystal Structure of an Unusual Betulin Amine Dimer1 ????J Nat Prod http://www.kidney.de/pget.php?&tw=1&pmid=24694263 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24694263 #FOAvip English Wikipedia <ref>{{Cite pmid|24694263}}</ref> Antineoplastic Agents 595 Structural Modifications of Betulin and the X-ray Crystal Structure of an Unusual Betulin Amine Dimer1 #MMPMID24694263 Pettit GR; Melody N; Hempenstall F; Chapuis JC; Groy TL; Williams L J Nat Prod 2014[Apr]; 77 (4): 863-72 PMID24694263show ga The lupane-type triterpene betulin (1) has been subjected to a series of structural modifications for the purpose of evaluating resultant cancer cell growth inhibitory activity. The reaction sequence 7 ? 11 ? 12 was especially noteworthy in providing a betulin-derived amine dimer. Other unexpected synthetic results included the 11 and 13/14 ? 17 conversions, which yielded an imidazo derivative. X-ray crystal structures of dimer 12 and intermediate 25 are reported. All of the betulin modifications were examined for anticancer activity against the P388 murine and human cell lines. Significant cancer cell growth inhibition was found for 4, 8, 9, 15/16, 19, 20, 24, and 26, which further defines the utility of the betulin scaffold. äAntineoplastic Agents 595 Structural Modifications of Betulin and th(epmc).pdf DeepDyve Pubget Overpricing