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10.1021/ml100092a http://scihub22266oqcxt.onion/10.1021/ml100092a C4007795!4007795 !24900209     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24900209 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       ACS+Med+Chem+Lett 2010 ; 1 (6 ): 286-9 Nephropedia Template TP {{tp|p=24900209 |t=2010. Synthesis and Biochemical Testing of 3-(Carboxyphenylethyl)imidazo 2,1-f 1,2,4 triazines as Inhibitors of AMP Deaminase |pdf=|usr=}}{{24900209 }} gab.com Text Synthesis and Biochemical Testing of 3-(Carboxyphenylethyl)imidazo 2,1-f 1,2,4 triazines as Inhibitors of AMP Deaminase JO: ACS Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=24900209 #FOAvip C-Ribosyl imidazo[2,1-f][1,2,4]triazines and 3-[2-(3-carboxyphenyl)ethyl]-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ols represent two classes of known AMP deaminase inhibitors. A combination of the aglycone from the former class with the ribose phosphate mimic from the latter led to the 3-[2-(3-carboxyphenyl)ethyl]imidazo[2,1-f][1,2,4]triazines, which represent a new class of AMP deaminase inhibitors. The best compound, 3-[2-(3-carboxy-5,6,7,8-tetrahydronaphthyl)ethyl]imidazo[2,1-f][1,2,4]triazine (8), was a good inhibitor of all three human AMPD recombinant isozymes (AMPD1, AMPD2, and AMPD3; IC50 = 0.9-5.7 ?M) but a poor inhibitor of the plant recombinant enzyme (Arabidopsis FAC1; IC50 = 200 ?M). Twit Text FOAVip Synthesis and Biochemical Testing of 3-(Carboxyphenylethyl)imidazo 2,1-f 1,2,4 triazines as Inhibitors of AMP Deaminase ????ACS Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=24900209 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24900209 #FOAvip English Wikipedia <ref>{{Cite pmid|24900209 }}</ref> Synthesis and Biochemical Testing of 3-(Carboxyphenylethyl)imidazo 2,1-f 1,2,4 triazines as Inhibitors of AMP Deaminase #MMPMID24900209 Lindell SD ; Maechling S ; Sabina RL ACS Med Chem Lett 2010[Sep]; 1 (6 ): 286-9 PMID24900209 show ga C-Ribosyl imidazo[2,1-f][1,2,4]triazines and 3-[2-(3-carboxyphenyl)ethyl]-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ols represent two classes of known AMP deaminase inhibitors. A combination of the aglycone from the former class with the ribose phosphate mimic from the latter led to the 3-[2-(3-carboxyphenyl)ethyl]imidazo[2,1-f][1,2,4]triazines, which represent a new class of AMP deaminase inhibitors. The best compound, 3-[2-(3-carboxy-5,6,7,8-tetrahydronaphthyl)ethyl]imidazo[2,1-f][1,2,4]triazine (8), was a good inhibitor of all three human AMPD recombinant isozymes (AMPD1, AMPD2, and AMPD3; IC50 = 0.9-5.7 ?M) but a poor inhibitor of the plant recombinant enzyme (Arabidopsis FAC1; IC50 = 200 ?M). äSynthesis and Biochemical Testing of 3-(Carboxyphenylethyl)imidazo 2(epmc).pdf DeepDyve Pubget Overpricing