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10.1074/jbc.M113.531095

http://scihub22266oqcxt.onion/10.1074/jbc.M113.531095
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suck abstract from ncbi


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pmid24610784      J+Biol+Chem 2014 ; 289 (17): 11791-806
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  • A Role for the Circadian Clock Protein Per1 in the Regulation of the NaCl Co-transporter (NCC) and the with-no-lysine Kinase (WNK) Cascade in Mouse Distal Convoluted Tubule Cells* #MMPMID24610784
  • Richards J; Ko B; All S; Cheng KY; Hoover RS; Gumz ML
  • J Biol Chem 2014[Apr]; 289 (17): 11791-806 PMID24610784show ga
  • Background: The role of the circadian protein Per1 in the regulation of sodium reabsorption in the distal convoluted tubule (DCT) is unknown.Results: Per1 transcriptionally regulates the sodium transporter NCC and the WNK kinase cascade.Conclusion: Per1 regulates sodium reabsorption in the DCT through NCC and the WNK cascade.Significance: These data demonstrate a role for Per1 in the regulation of renal sodium transporters.
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