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A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1002/embj.201386942 http://scihub22266oqcxt.onion/10.1002/embj.201386942 C4000088!4000088 !24562386     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24562386 &cmd=llinks): Failed to open stream: HTTP request failed! 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A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures |pdf=|usr=}}{{24562386 }} gab.com Text A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures JO: EMBO J http://www.kidney.de/pget.php?&tw=1&pmid=24562386 #FOAvip Growth factor-dependent epithelial morphological changes and proliferation are essential for the formation of tubular structures, but the underlying molecular mechanisms are poorly understood. Co-stimulation with Wnt3a and epidermal growth factor (Wnt3a/EGF) induced development of tubes consisting of intestinal epithelial cells by inducing expression of Arl4c, an Arf-like small GTP-binding protein, in three-dimensional culture, while stimulation with Wnt3a or EGF alone did not. Arl4c expression resulted in rearrangement of the cytoskeleton through activation of Rac and inactivation of Rho properly, which promoted cell growth by inducing nuclear translocation of Yes-associated protein and transcriptional co-activator with PDZ-binding motif (YAP/TAZ) in leading cells. Arl4c was expressed in ureteric bud tips and pretubular structures in the embryonic kidney. In an organoid culture assay, Wnt and fibroblast growth factor signaling simultaneously induced elongation and budding of kidney ureteric buds through Arl4c expression. YAP/TAZ was observed in the nucleus of extending ureteric bud tips. Thus, Arl4c expression induced by a combination of growth factor signaling mechanisms is involved in tube formation. Twit Text FOAVip A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures ????EMBO J http://www.kidney.de/pget.php?&tw=1&pmid=24562386 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24562386 #FOAvip English Wikipedia <ref>{{Cite pmid|24562386 }}</ref> A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures #MMPMID24562386 Matsumoto S ; Fujii S ; Sato A ; Ibuka S ; Kagawa Y ; Ishii M ; Kikuchi A EMBO J 2014[Apr]; 33 (7 ): 702-18 PMID24562386 show ga Growth factor-dependent epithelial morphological changes and proliferation are essential for the formation of tubular structures, but the underlying molecular mechanisms are poorly understood. Co-stimulation with Wnt3a and epidermal growth factor (Wnt3a/EGF) induced development of tubes consisting of intestinal epithelial cells by inducing expression of Arl4c, an Arf-like small GTP-binding protein, in three-dimensional culture, while stimulation with Wnt3a or EGF alone did not. Arl4c expression resulted in rearrangement of the cytoskeleton through activation of Rac and inactivation of Rho properly, which promoted cell growth by inducing nuclear translocation of Yes-associated protein and transcriptional co-activator with PDZ-binding motif (YAP/TAZ) in leading cells. Arl4c was expressed in ureteric bud tips and pretubular structures in the embryonic kidney. In an organoid culture assay, Wnt and fibroblast growth factor signaling simultaneously induced elongation and budding of kidney ureteric buds through Arl4c expression. YAP/TAZ was observed in the nucleus of extending ureteric bud tips. Thus, Arl4c expression induced by a combination of growth factor signaling mechanisms is involved in tube formation. |*Signal Transduction [MESH] |ADP-Ribosylation Factors/*metabolism [MESH] |Acyltransferases [MESH] |Animals [MESH] |Cell Adhesion [MESH] |Cell Differentiation [MESH] |Cells, Cultured [MESH] |Cytoskeleton/metabolism [MESH] |Dogs [MESH] |Epidermal Growth Factor/*metabolism [MESH] |Epithelial Cells/cytology/physiology [MESH] |Female [MESH] |Fetus [MESH] |Fibroblast Growth Factors/metabolism [MESH] |HeLa Cells [MESH] |Humans [MESH] |Intestinal Mucosa/metabolism [MESH] |Intestines/cytology [MESH] |Kidney/embryology [MESH] |Madin Darby Canine Kidney Cells [MESH] |Mice [MESH] |Mice, Inbred C57BL [MESH] |Rats [MESH] |Transcription Factors/*metabolism [MESH]A combination of Wnt and growth factor signaling induces Arl4c express(epmc).pdf DeepDyve Pubget Overpricing