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10.1101/cshperspect.a016725

http://scihub22266oqcxt.onion/10.1101/cshperspect.a016725
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C3996469!3996469!24789820
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suck abstract from ncbi


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pmid24789820      Cold+Spring+Harb+Perspect+Biol 2014 ; 6 (5): ä
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  • Molecular Structure, Function, and Dynamics of Clathrin-Mediated Membrane Traffic #MMPMID24789820
  • Kirchhausen T; Owen D; Harrison SC
  • Cold Spring Harb Perspect Biol 2014[May]; 6 (5): ä PMID24789820show ga
  • Clathrin is a molecular scaffold for vesicular uptake of cargo at the plasma membrane, where its assembly into cage-like lattices underlies the clathrin-coated pits of classical endocytosis. This review describes the structures of clathrin, major cargo adaptors, and other proteins that participate in forming a clathrin-coated pit, loading its contents, pinching off the membrane as a lattice-enclosed vesicle, and recycling the components. It integrates as much of the structural information as possible at the time of writing into a sketch of the principal steps in coated-pit and coated-vesicle formation.
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