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10.1101/cshperspect.a015404 http://scihub22266oqcxt.onion/10.1101/cshperspect.a015404 C3996376!3996376!24789873     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cold+Spring+Harb+Perspect+Med 2014 ; 4 (5): ä Nephropedia Template TP {{tp|p=24789873|t=2014. Long Noncoding RNA: Significance and Potential in Skin Biology |pdf=|usr=}}{{24789873}} gab.com Text Long Noncoding RNA: Significance and Potential in Skin Biology JO: Cold Spring Harb Perspect Med http://www.kidney.de/pget.php?&tw=1&pmid=24789873 #FOAvip Over the past few years, advances in genome analyses have identified an emerging class of noncoding RNAs that play critical roles in the regulation of gene expression and epigenetic reprogramming. Given their transcriptional pervasiveness, the potential for these intriguing macromolecules to integrate a myriad of external cellular cues with nuclear responses has become increasingly apparent. Recent studies have implicated noncoding RNAs in epidermal development and keratinocyte differentiation, but the complexity of multilevel regulation of transcriptional programs involved in these processes remains ill defined. In this review, we discuss the relevance of noncoding RNA in normal skin development, their involvement in cutaneous malignancies, and their role in the regulation of adult stem-cell maintenance in stratified epithelial tissues. Furthermore, we provide additional examples highlighting the ubiquity of noncoding RNAs in diverse human diseases. Twit Text FOAVip Long Noncoding RNA: Significance and Potential in Skin Biology ????Cold Spring Harb Perspect Med http://www.kidney.de/pget.php?&tw=1&pmid=24789873 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24789873 #FOAvip English Wikipedia <ref>{{Cite pmid|24789873}}</ref> Long Noncoding RNA: Significance and Potential in Skin Biology #MMPMID24789873 Wan DC; Wang KC Cold Spring Harb Perspect Med 2014[May]; 4 (5): ä PMID24789873show ga Over the past few years, advances in genome analyses have identified an emerging class of noncoding RNAs that play critical roles in the regulation of gene expression and epigenetic reprogramming. Given their transcriptional pervasiveness, the potential for these intriguing macromolecules to integrate a myriad of external cellular cues with nuclear responses has become increasingly apparent. Recent studies have implicated noncoding RNAs in epidermal development and keratinocyte differentiation, but the complexity of multilevel regulation of transcriptional programs involved in these processes remains ill defined. In this review, we discuss the relevance of noncoding RNA in normal skin development, their involvement in cutaneous malignancies, and their role in the regulation of adult stem-cell maintenance in stratified epithelial tissues. Furthermore, we provide additional examples highlighting the ubiquity of noncoding RNAs in diverse human diseases. äLong Noncoding RNA: Significance and Potential in Skin Biology (epmc).pdf DeepDyve Pubget Overpricing