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10.1016/j.spinee.2013.07.468

http://scihub22266oqcxt.onion/10.1016/j.spinee.2013.07.468
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C3989479!3989479!24139233
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suck abstract from ncbi


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pmid24139233      Spine+J 2014 ; 14 (7): 1106-16
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  • Dose-Response and Efficacy of Spinal Manipulation for Care of Chronic Low Back Pain: A Randomized Controlled Trial #MMPMID24139233
  • Haas M; Vavrek D; Peterson D; Polissar N; Neradilek MB
  • Spine J 2014[Jul]; 14 (7): 1106-16 PMID24139233show ga
  • BACKGROUND CONTEXT: There have been no full-scale trials of the optimal number of visits for the care of any condition with spinal manipulation. PURPOSE: To identify the dose-response relationship between visits to a chiropractor for spinal manipulation and chronic low back pain (cLBP) outcomes; to determine the efficacy of manipulation by comparison to a light-massage control. STUDY DESIGN/SETTING: Practice-based randomized controlled trial. PATIENT SAMPLE: Four hundred participants with cLBP. OUTCOME MEASURES: The primary cLBP outcomes were the100-point Modified Von Korff pain intensity and functional disability scales evaluated at the 12 and 24-week primary endpoints. Secondary outcomes included days with pain and functional disability, pain unpleasantness, global perceived improvement, medication use, and general health status. METHODS: One hundred participants with cLBP were randomized to each of four dose levels of care: 0, 6, 12, or 18 sessions of spinal manipulation from a chiropractor. Participants were treated three times per week for six weeks. At sessions when manipulation was not assigned, they received a focused light massage control. Covariate-adjusted linear dose effects and comparisons to the no-manipulation control group were evaluated at 6, 12, 18, 24, 39, and 52 weeks. RESULTS: For the primary outcomes, mean pain and disability improvement in the manipulation groups was 20 points by 12 weeks and sustainable to 52 weeks. Linear dose-response effects were small, reaching about two points per six manipulation sessions at 12 and 52 weeks for both variables (P < .025). At 12 weeks, the greatest differences from the no-manipulation control were found for 12 sessions (8.6 pain and 7.6 disability points, P < .025); at 24 weeks, differences were negligible. At 52 weeks, the greatest group differences were seen for 18 visits (5.9 pain and 8.8 disability points, P < .025). CONCLUSIONS: The number of spinal manipulation visits had modest effects on cLBP outcomes above those of 18 hands-on visits to a chiropractor. Overall, 12 visits yielded the most favorable results, but was not well distinguished from other dose levels.
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