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10.1016/j.febslet.2014.02.008 http://scihub22266oqcxt.onion/10.1016/j.febslet.2014.02.008 C3989410!3989410!24548564     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       FEBS+Lett 2014 ; 588 (8): 1322-30 Nephropedia Template TP {{tp|p=24548564|t=2014. Arrhythmogenic Cardiomyopathy and Brugada Syndrome: Diseases of the connexome |pdf=|usr=}}{{24548564}} gab.com Text Arrhythmogenic Cardiomyopathy and Brugada Syndrome: Diseases of the connexome JO: FEBS Lett http://www.kidney.de/pget.php?&tw=1&pmid=24548564 #FOAvip This review summarizes data in support of the notion that the cardiac intercalated disc is the host of a protein interacting network, called ?the connexome,? where molecules classically defined as belonging to one particular structure (e.g., desmosomes, gap junctions, sodium channel complex) actually interact with others, and together, control excitability, electrical coupling and intercellular adhesion in the heart. The concept of the connexome is then translated into the understanding of the mechanisms leading to two inherited arrhythmia diseases: Arrhythmogenic Cardiomyopathy, and Brugada syndrome. The cross-over points in these two diseases are addressed to then suggest that, though separate identifiable clinical entities, they represent ?bookends? of a spectrum of manifestations that vary depending on the effect that a particular mutation has on the connexome as a whole. Twit Text FOAVip Arrhythmogenic Cardiomyopathy and Brugada Syndrome: Diseases of the connexome ????FEBS Lett http://www.kidney.de/pget.php?&tw=1&pmid=24548564 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24548564 #FOAvip English Wikipedia <ref>{{Cite pmid|24548564}}</ref> Arrhythmogenic Cardiomyopathy and Brugada Syndrome: Diseases of the connexome #MMPMID24548564 Agullo-Pascual E; Cerrone M; Delmar M FEBS Lett 2014[Apr]; 588 (8): 1322-30 PMID24548564show ga This review summarizes data in support of the notion that the cardiac intercalated disc is the host of a protein interacting network, called ?the connexome,? where molecules classically defined as belonging to one particular structure (e.g., desmosomes, gap junctions, sodium channel complex) actually interact with others, and together, control excitability, electrical coupling and intercellular adhesion in the heart. The concept of the connexome is then translated into the understanding of the mechanisms leading to two inherited arrhythmia diseases: Arrhythmogenic Cardiomyopathy, and Brugada syndrome. The cross-over points in these two diseases are addressed to then suggest that, though separate identifiable clinical entities, they represent ?bookends? of a spectrum of manifestations that vary depending on the effect that a particular mutation has on the connexome as a whole. äArrhythmogenic Cardiomyopathy and Brugada Syndrome: Diseases of the co(epmc).pdf DeepDyve Pubget Overpricing