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10.1534/genetics.114.161364 http://scihub22266oqcxt.onion/10.1534/genetics.114.161364 C3982689!3982689!24496012     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genetics 2014 ; 196 (4): 1185-97 Nephropedia Template TP {{tp|p=24496012|t=2014. The Evolution of Phenotypic Switching in Subdivided Populations |pdf=|usr=}}{{24496012}} gab.com Text The Evolution of Phenotypic Switching in Subdivided Populations JO: Genetics http://www.kidney.de/pget.php?&tw=1&pmid=24496012 #FOAvip Stochastic switching is an example of phenotypic bet hedging, where offspring can express a phenotype different from that of their parents. Phenotypic switching is well documented in viruses, yeast, and bacteria and has been extensively studied when the selection pressures vary through time. However, there has been little work on the evolution of phenotypic switching under both spatially and temporally fluctuating selection pressures. Here we use a population genetic model to explore the interaction of temporal and spatial variation in determining the evolutionary dynamics of phenotypic switching. We find that the stable switching rate is mainly determined by the rate of environmental change and the migration rate. This stable rate is also a decreasing function of the recombination rate, although this is a weaker effect than those of either the period of environmental change or the migration rate. This study highlights the interplay of spatial and temporal environmental variability, offering new insights into how migration can influence the evolution of phenotypic switching rates, mutation rates, or other sources of phenotypic variation. Twit Text FOAVip The Evolution of Phenotypic Switching in Subdivided Populations ????Genetics http://www.kidney.de/pget.php?&tw=1&pmid=24496012 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24496012 #FOAvip English Wikipedia <ref>{{Cite pmid|24496012}}</ref> The Evolution of Phenotypic Switching in Subdivided Populations #MMPMID24496012 Carja O; Liberman U; Feldman MW Genetics 2014[Apr]; 196 (4): 1185-97 PMID24496012show ga Stochastic switching is an example of phenotypic bet hedging, where offspring can express a phenotype different from that of their parents. Phenotypic switching is well documented in viruses, yeast, and bacteria and has been extensively studied when the selection pressures vary through time. However, there has been little work on the evolution of phenotypic switching under both spatially and temporally fluctuating selection pressures. Here we use a population genetic model to explore the interaction of temporal and spatial variation in determining the evolutionary dynamics of phenotypic switching. We find that the stable switching rate is mainly determined by the rate of environmental change and the migration rate. This stable rate is also a decreasing function of the recombination rate, although this is a weaker effect than those of either the period of environmental change or the migration rate. This study highlights the interplay of spatial and temporal environmental variability, offering new insights into how migration can influence the evolution of phenotypic switching rates, mutation rates, or other sources of phenotypic variation. äThe Evolution of Phenotypic Switching in Subdivided Populations (epmc).pdf DeepDyve Pubget Overpricing