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10.1074/jbc.M113.540948

http://scihub22266oqcxt.onion/10.1074/jbc.M113.540948
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C3975042!3975042!24526686
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suck abstract from ncbi


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pmid24526686      J+Biol+Chem 2014 ; 289 (14): 9983-97
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  • Annexin A2 Mediates Apical Trafficking of Renal Na+-K+-2Cl? Cotransporter* #MMPMID24526686
  • Dathe C; Daigeler AL; Seifert W; Jankowski V; Mrowka R; Kalis R; Wanker E; Mutig K; Bachmann S; Paliege A
  • J Biol Chem 2014[Apr]; 289 (14): 9983-97 PMID24526686show ga
  • Background: Regulated membrane expression of the renal furosemide-sensitive Na+-K+-2Cl? cotransporter (NKCC2) determines essential functions of the kidney.Results: Annexin A2 (AnxA2) is a new interaction partner of NKCC2 with respect to its adluminal trafficking and activation.Conclusion: Discussion focuses on trafficking, membrane association, and phosphorylation of NKCC2 and its cellular ligand AnxA2.Significance: AnxA2 is relevant for the activation of NKCC2.
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