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10.1074/jbc.M113.545822 http://scihub22266oqcxt.onion/10.1074/jbc.M113.545822 C3975039!3975039!24550394     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 310.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2014 ; 289 (14): 9952-60 Nephropedia Template TP {{tp|p=24550394|t=2014. Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-? (TGF-?) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein |pdf=|usr=}}{{24550394}} gab.com Text Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor- (TGF- ) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24550394 #FOAvip Background: IL-6 is a profibrotic molecule, but the mechanism is unclear.Results: IL-6 mediates fibrosis via a STAT3- and Smad3-dependent pathway mediated via a novel cytokine, Gremlin.Conclusion: A novel pathway of IL-6 mediated fibrogenesis has been defined.Significance: Targeting Gremlin is a new therapeutic target in fibrosis downstream of STAT3. Twit Text FOAVip Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor- (TGF- ) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24550394 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24550394 #FOAvip English Wikipedia <ref>{{Cite pmid|24550394}}</ref> Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-? (TGF-?) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein #MMPMID24550394 O'Reilly S; Ciechomska M; Cant R; van Laar JM J Biol Chem 2014[Apr]; 289 (14): 9952-60 PMID24550394show ga Background: IL-6 is a profibrotic molecule, but the mechanism is unclear.Results: IL-6 mediates fibrosis via a STAT3- and Smad3-dependent pathway mediated via a novel cytokine, Gremlin.Conclusion: A novel pathway of IL-6 mediated fibrogenesis has been defined.Significance: Targeting Gremlin is a new therapeutic target in fibrosis downstream of STAT3. äInterleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway (epmc).pdf DeepDyve Pubget Overpricing