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10.1124/pr.112.007351 http://scihub22266oqcxt.onion/10.1124/pr.112.007351 C3973613!3973613!24671377     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmacol+Rev 2014 ; 66 (2): 513-69 Nephropedia Template TP {{tp|p=24671377|t=2014. Regulation of Cellular Communication by Signaling Microdomains in the Blood Vessel Wall |pdf=|usr=}}{{24671377}} gab.com Text Regulation of Cellular Communication by Signaling Microdomains in the Blood Vessel Wall JO: Pharmacol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24671377 #FOAvip It has become increasingly clear that the accumulation of proteins in specific regions of the plasma membrane can facilitate cellular communication. These regions, termed signaling microdomains, are found throughout the blood vessel wall where cellular communication, both within and between cell types, must be tightly regulated to maintain proper vascular function. We will define a cellular signaling microdomain and apply this definition to the plethora of means by which cellular communication has been hypothesized to occur in the blood vessel wall. To that end, we make a case for three broad areas of cellular communication where signaling microdomains could play an important role: 1) paracrine release of free radicals and gaseous molecules such as nitric oxide and reactive oxygen species; 2) role of ion channels including gap junctions and potassium channels, especially those associated with the endothelium-derived hyperpolarization mediated signaling, and lastly, 3) mechanism of exocytosis that has considerable oversight by signaling microdomains, especially those associated with the release of von Willebrand factor. When summed, we believe that it is clear that the organization and regulation of signaling microdomains is an essential component to vessel wall function. Twit Text FOAVip Regulation of Cellular Communication by Signaling Microdomains in the Blood Vessel Wall ????Pharmacol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24671377 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24671377 #FOAvip English Wikipedia <ref>{{Cite pmid|24671377}}</ref> Regulation of Cellular Communication by Signaling Microdomains in the Blood Vessel Wall #MMPMID24671377 Billaud M; Lohman AW; Johnstone SR; Biwer LA; Mutchler S; Isakson BE Pharmacol Rev 2014[Apr]; 66 (2): 513-69 PMID24671377show ga It has become increasingly clear that the accumulation of proteins in specific regions of the plasma membrane can facilitate cellular communication. These regions, termed signaling microdomains, are found throughout the blood vessel wall where cellular communication, both within and between cell types, must be tightly regulated to maintain proper vascular function. We will define a cellular signaling microdomain and apply this definition to the plethora of means by which cellular communication has been hypothesized to occur in the blood vessel wall. To that end, we make a case for three broad areas of cellular communication where signaling microdomains could play an important role: 1) paracrine release of free radicals and gaseous molecules such as nitric oxide and reactive oxygen species; 2) role of ion channels including gap junctions and potassium channels, especially those associated with the endothelium-derived hyperpolarization mediated signaling, and lastly, 3) mechanism of exocytosis that has considerable oversight by signaling microdomains, especially those associated with the release of von Willebrand factor. When summed, we believe that it is clear that the organization and regulation of signaling microdomains is an essential component to vessel wall function. äRegulation of Cellular Communication by Signaling Microdomains in the (epmc).pdf DeepDyve Pubget Overpricing