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10.1111/bcp.12208

http://scihub22266oqcxt.onion/10.1111/bcp.12208
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C3971979!3971979!23834499
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suck abstract from ncbi

pmid23834499      Br+J+Clin+Pharmacol 2014 ; 77 (4): 618-25
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  • The genetics of pro-arrhythmic adverse drug reactions #MMPMID23834499
  • Petropoulou E; Jamshidi Y; Behr ER
  • Br J Clin Pharmacol 2014[Apr]; 77 (4): 618-25 PMID23834499show ga
  • Ventricular arrhythmia induced by drugs (pro-arrythmia) is an uncommon event, whose occurrence is unpredictable but potentially fatal. The ability of a variety of medications to induce these arrhythmias is a significant problem facing the pharmaceutical industry. Genetic variants have been shown to play a role in adverse events and are also known to influence an individual's optimal drug dose. This review provides an overview of the current understanding of the role of genetic variants in modulating the risk of drug induced arrhythmias.
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