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10.4049/jimmunol.1302934 http://scihub22266oqcxt.onion/10.4049/jimmunol.1302934 C3967505!3967505!24563255     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunol 2014 ; 192 (7): 3021-8 Nephropedia Template TP {{tp|p=24563255|t=2014. Inhibitory Fc? receptor is required for the maintenance of tolerance through distinct mechanisms1 |pdf=|usr=}}{{24563255}} gab.com Text Inhibitory Fc receptor is required for the maintenance of tolerance through distinct mechanisms1 JO: J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24563255 #FOAvip The inhibitory Fc? receptor, Fc?RIIB, is widely expressed on B cells, dendritic cells and myeloid effector cells and modulates a variety of antibody-driven in vivo functions. While it has been established that Fc?RIIB plays an important role in the maintenance of peripheral tolerance, the responsible cell-specific Fc?RIIB expression remains to be determined. In this study, we generated mice with selective deletion of Fc?RIIB in B cells, dendritic cells and myeloid effector cells and evaluated these novel strains in models of tolerance and autoimmune diseases. Our results demonstrate that mice with selective deletion of Fc?RIIB expression in B cells and dendritic cells have increased antibody and T cell responses, respectively, and display enhanced susceptibility to disease in distinct models, suggesting that Fc?RIIB expression in distinct cellular populations contributes to the maintenance of peripheral tolerance through different mechanisms. Twit Text FOAVip Inhibitory Fc receptor is required for the maintenance of tolerance through distinct mechanisms1 ????J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24563255 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24563255 #FOAvip English Wikipedia <ref>{{Cite pmid|24563255}}</ref> Inhibitory Fc? receptor is required for the maintenance of tolerance through distinct mechanisms1 #MMPMID24563255 Li F; Smith P; Ravetch JV J Immunol 2014[Apr]; 192 (7): 3021-8 PMID24563255show ga The inhibitory Fc? receptor, Fc?RIIB, is widely expressed on B cells, dendritic cells and myeloid effector cells and modulates a variety of antibody-driven in vivo functions. While it has been established that Fc?RIIB plays an important role in the maintenance of peripheral tolerance, the responsible cell-specific Fc?RIIB expression remains to be determined. In this study, we generated mice with selective deletion of Fc?RIIB in B cells, dendritic cells and myeloid effector cells and evaluated these novel strains in models of tolerance and autoimmune diseases. Our results demonstrate that mice with selective deletion of Fc?RIIB expression in B cells and dendritic cells have increased antibody and T cell responses, respectively, and display enhanced susceptibility to disease in distinct models, suggesting that Fc?RIIB expression in distinct cellular populations contributes to the maintenance of peripheral tolerance through different mechanisms. äInhibitory Fc? receptor is required for the maintenance of tolerance t(epmc).pdf DeepDyve Pubget Overpricing