Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.4049/jimmunol.1400003 http://scihub22266oqcxt.onion/10.4049/jimmunol.1400003 C3965619!3965619!24600038     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunol 2014 ; 192 (7): 2961-4 Nephropedia Template TP {{tp|p=24600038|t=2014. Resident memory CD8 T cells occupy frontline niches in secondary lymphoid organs |pdf=|usr=}}{{24600038}} gab.com Text Resident memory CD8 T cells occupy frontline niches in secondary lymphoid organs JO: J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24600038 #FOAvip Resident memory CD8 T cells (TRM) comprise a non-recirculating subset positioned in non-lymphoid tissues (NLT) to provide early responses to re-infection. While TRM are associated with NLT, we asked whether they populated secondary lymphoid organs (SLO). We show that a subset of virus specific memory CD8 T cells in SLO exhibit phenotypic signatures associated with TRM, including CD69 expression. Parabiosis revealed that SLO CD69+ memory CD8 T cells do not circulate, defining them as TRM. SLO TRM were overrepresented in IL-15 deficient mice, suggesting independent regulation compared to TCM and TEM. These cells were positioned at SLO entry points for peripheral antigens: the splenic marginal zone, red pulp, and lymph node sinuses. Consistent with a potential role in guarding SLO pathogen entry points, SLO TRM did not vacate their position in response to peripheral alarm signals. These data extend the range of tissue resident memory to SLO. Twit Text FOAVip Resident memory CD8 T cells occupy frontline niches in secondary lymphoid organs ????J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24600038 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24600038 #FOAvip English Wikipedia <ref>{{Cite pmid|24600038}}</ref> Resident memory CD8 T cells occupy frontline niches in secondary lymphoid organs #MMPMID24600038 Schenkel JM; Fraser KA; Masopust D J Immunol 2014[Apr]; 192 (7): 2961-4 PMID24600038show ga Resident memory CD8 T cells (TRM) comprise a non-recirculating subset positioned in non-lymphoid tissues (NLT) to provide early responses to re-infection. While TRM are associated with NLT, we asked whether they populated secondary lymphoid organs (SLO). We show that a subset of virus specific memory CD8 T cells in SLO exhibit phenotypic signatures associated with TRM, including CD69 expression. Parabiosis revealed that SLO CD69+ memory CD8 T cells do not circulate, defining them as TRM. SLO TRM were overrepresented in IL-15 deficient mice, suggesting independent regulation compared to TCM and TEM. These cells were positioned at SLO entry points for peripheral antigens: the splenic marginal zone, red pulp, and lymph node sinuses. Consistent with a potential role in guarding SLO pathogen entry points, SLO TRM did not vacate their position in response to peripheral alarm signals. These data extend the range of tissue resident memory to SLO. äResident memory CD8 T cells occupy frontline niches in secondary lymph(epmc).pdf DeepDyve Pubget Overpricing