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10.2105/AJPH.2013.301549

http://scihub22266oqcxt.onion/10.2105/AJPH.2013.301549
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suck abstract from ncbi


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pmid24432883
      Am+J+Public+Health 2014 ; 104 (3 ): 474-81
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  • Previous exposure to HCV among persons born during 1945-1965: prevalence and predictors, United States, 1999-2008 #MMPMID24432883
  • Smith BD ; Beckett GA ; Yartel A ; Holtzman D ; Patel N ; Ward JW
  • Am J Public Health 2014[Mar]; 104 (3 ): 474-81 PMID24432883 show ga
  • OBJECTIVES: We examined HCV exposure prevalence and predictors among persons in the United States born during 1945-1965. METHODS: With data from the 1999-2008 National Health and Nutrition Examination Survey, we calculated the proportion of persons born during 1945-1965 who tested positive for HCV antibody (anti-HCV) and analyzed the prevalence by sociodemographic and behavioral risk factors. RESULTS: Anti-HCV prevalence in the 1945-1965 birth cohort was 3.2% (95% confidence interval [CI]?=?2.8%, 3.8%), substantially higher than among other adults (0.9%). Within the cohort, anti-HCV prevalence was higher among non-Hispanic Blacks (6.4%; 95% CI?=?5.3%, 7.7%), persons with injection drug use histories (56.8%; 95% CI?=?48.4%, 64.8%), and persons with elevated alanine aminotransferase levels (12.7%; 95% CI?=?10.7%, 15.1%). Injection drug use (adjusted odds ratio?=?98.4; 95% CI?=?58.8, 164.5) was the strongest anti-HCV prevalence predictor. Among anti-HCV-positive persons, 57.8% reported having 2 or more alcoholic drinks daily. CONCLUSIONS: With the high prevalence of HCV among persons born during 1945-1965, the increasing morbidity and mortality associated with HCV, and reductions in liver cancer and HCV-related mortality when HCV is eradicated, it is critically important to identify persons with HCV and link them to appropriate care.
  • |*Hepacivirus [MESH]
  • |Adult [MESH]
  • |Aged [MESH]
  • |Cohort Studies [MESH]
  • |Confidence Intervals [MESH]
  • |Female [MESH]
  • |Forecasting [MESH]
  • |Health Surveys [MESH]
  • |Hepatitis C Antibodies/*isolation & purification [MESH]
  • |Hepatitis C/complications/*epidemiology [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Nutrition Surveys [MESH]
  • |Prevalence [MESH]
  • |Risk Factors [MESH]


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