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10.1111/j.1582-4934.2011.01299.x http://scihub22266oqcxt.onion/10.1111/j.1582-4934.2011.01299.x C3922684!3922684!21426485     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cell+Mol+Med 2011 ; 15 (4): 1005-11 Nephropedia Template TP {{tp|p=21426485|t=2011. Heterocellular communication in the heart: electron tomography of telocyte?myocyte junctions |pdf=|usr=}}{{21426485}} gab.com Text Heterocellular communication in the heart: electron tomography of telocyte myocyte junctions JO: J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=21426485 #FOAvip Myocardium is composed of two main cell populations: cardiomyocytes (CMs) and interstitial cells (e.g. fibroblasts, immunoreactive cells, capillaries). However, very recently we have showed that a novel type of interstitial cell called telocytes (TCs) does exist in epi-, myo- and endocardium. They have very long and thin telopodes (Tp) formed by alternating podomeres and podoms. Heterocellular communication between TCs and CMs it is supposed to occur by shed vesicles and close apposition. If TCs have to play a role in cardiac physiology it is expected to develop direct and unambiguous contacts with CMs. Because a clear membrane-to-membrane junction has not been reported by electron microscopy we have investigated the heterocellular communication in the mouse heart by electron tomography. This advanced technique showed that small dense structures (10?15 nm nanocontacts) directly connect TCs with CMs. More complex and atypical junctions could be observed between TCs and CMs at the level of intercalated discs. This study proves that TCs and CMs are directly connected and might represent a ?functional unit?. Twit Text FOAVip Heterocellular communication in the heart: electron tomography of telocyte myocyte junctions ????J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=21426485 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21426485 #FOAvip English Wikipedia <ref>{{Cite pmid|21426485}}</ref> Heterocellular communication in the heart: electron tomography of telocyte?myocyte junctions #MMPMID21426485 Gherghiceanu M; Popescu LM J Cell Mol Med 2011[Apr]; 15 (4): 1005-11 PMID21426485show ga Myocardium is composed of two main cell populations: cardiomyocytes (CMs) and interstitial cells (e.g. fibroblasts, immunoreactive cells, capillaries). However, very recently we have showed that a novel type of interstitial cell called telocytes (TCs) does exist in epi-, myo- and endocardium. They have very long and thin telopodes (Tp) formed by alternating podomeres and podoms. Heterocellular communication between TCs and CMs it is supposed to occur by shed vesicles and close apposition. If TCs have to play a role in cardiac physiology it is expected to develop direct and unambiguous contacts with CMs. Because a clear membrane-to-membrane junction has not been reported by electron microscopy we have investigated the heterocellular communication in the mouse heart by electron tomography. This advanced technique showed that small dense structures (10?15 nm nanocontacts) directly connect TCs with CMs. More complex and atypical junctions could be observed between TCs and CMs at the level of intercalated discs. This study proves that TCs and CMs are directly connected and might represent a ?functional unit?. äHeterocellular communication in the heart: electron tomography of telo(epmc).pdf DeepDyve Pubget Overpricing