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10.1007/s00467-013-2531-7 http://scihub22266oqcxt.onion/10.1007/s00467-013-2531-7 C3809028!3809028 !23748364     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=23748364 &cmd=llinks): Failed to open stream: HTTP request failed! 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The impact of APOL1, CAV1, and ABCB1 gene variants on outcomes in kidney transplantation: donor and recipient effects |pdf=|usr=}}{{23748364 }} gab.com Text The impact of APOL1, CAV1, and ABCB1 gene variants on outcomes in kidney transplantation: donor and recipient effects JO: Pediatr Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=23748364 #FOAvip Dramatic improvements have been seen in short-term kidney allograft survival over recent decades with introduction of more potent immunosuppressant medications and regimens. Unfortunately, improvements in long-term graft survival have lagged behind. The genomics revolution is providing new insights regarding the potential impact of kidney donor genotypes on long-term graft survival. Variation in the donor apolipoprotein L1 (APOL1), caveolin 1 (CAV1), and multi-drug resistance 1 encoding P-glycoprotein genes (ABCB1) are all associated with graft survival after kidney transplantation. Although the precise mechanisms whereby these donor gene variants confer risk for graft loss have yet to be determined, these findings provide novel opportunities for modifying interactive environmental factors and optimizing kidney allocation with the ultimate goal of improving long-term graft survival rates. Twit Text FOAVip The impact of APOL1, CAV1, and ABCB1 gene variants on outcomes in kidney transplantation: donor and recipient effects ????Pediatr Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=23748364 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23748364 #FOAvip English Wikipedia <ref>{{Cite pmid|23748364 }}</ref> The impact of APOL1, CAV1, and ABCB1 gene variants on outcomes in kidney transplantation: donor and recipient effects #MMPMID23748364 Palanisamy A ; Reeves-Daniel AM ; Freedman BI Pediatr Nephrol 2014[Sep]; 29 (9 ): 1485-92 PMID23748364 show ga Dramatic improvements have been seen in short-term kidney allograft survival over recent decades with introduction of more potent immunosuppressant medications and regimens. Unfortunately, improvements in long-term graft survival have lagged behind. The genomics revolution is providing new insights regarding the potential impact of kidney donor genotypes on long-term graft survival. Variation in the donor apolipoprotein L1 (APOL1), caveolin 1 (CAV1), and multi-drug resistance 1 encoding P-glycoprotein genes (ABCB1) are all associated with graft survival after kidney transplantation. Although the precise mechanisms whereby these donor gene variants confer risk for graft loss have yet to be determined, these findings provide novel opportunities for modifying interactive environmental factors and optimizing kidney allocation with the ultimate goal of improving long-term graft survival rates. |ATP Binding Cassette Transporter, Subfamily B/genetics [MESH] |Apolipoprotein L1 [MESH] |Apolipoproteins/*genetics [MESH] |Caveolin 1/*genetics [MESH] |Genotype [MESH] |Graft Survival/*genetics [MESH] |Humans [MESH] |Kidney Transplantation/*mortality [MESH] |Lipoproteins, HDL/*genetics [MESH]The impact of APOL1, CAV1, and ABCB1 gene variants on outcomes in kidn(epmc).pdf DeepDyve Pubget Overpricing