Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1097/NEN.0b013e3182945bf6 http://scihub22266oqcxt.onion/10.1097/NEN.0b013e3182945bf6 C3761353!3761353!23656993     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Neuropathol+Exp+Neurol 2013 ; 72 (6): 505-23 Nephropedia Template TP {{tp|p=23656993|t=2013. Disconnection of the Ascending Arousal System in Traumatic Coma |pdf=|usr=}}{{23656993}} gab.com Text Disconnection of the Ascending Arousal System in Traumatic Coma JO: J Neuropathol Exp Neurol http://www.kidney.de/pget.php?&tw=1&pmid=23656993 #FOAvip Traumatic coma is associated with disruption of axonal pathways throughout the brain but the specific pathways involved in humans are incompletely understood. In this study, we used high angular resolution diffusion imaging (HARDI) to map the connectivity of axonal pathways that mediate the 2 critical components of consciousness ? arousal and awareness ? in the postmortem brain of a 62-year-old woman with acute traumatic coma and in 2 control brains. HARDI tractography guided tissue sampling in the neuropathological analysis. HARDI tractography demonstrated complete disruption of white matter pathways connecting brainstem arousal nuclei to the basal forebrain and thalamic intralaminar and reticular nuclei. In contrast, hemispheric arousal pathways connecting the thalamus and basal forebrain to the cerebral cortex were only partially disrupted, as were the cortical ?awareness pathways.? Neuropathologic examination, which utilized ?-amyloid precursor protein and fractin immunomarkers, revealed axonal injury in the white matter of the brainstem and cerebral hemispheres that corresponded to sites of HARDI tract disruption. Axonal injury was also present within the grey matter of the hypothalamus, thalamus, basal forebrain, and cerebral cortex. We propose that traumatic coma may be a subcortical disconnection syndrome related to the disconnection of specific brainstem arousal nuclei from the thalamus and basal forebrain. Twit Text FOAVip Disconnection of the Ascending Arousal System in Traumatic Coma ????J Neuropathol Exp Neurol http://www.kidney.de/pget.php?&tw=1&pmid=23656993 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23656993 #FOAvip English Wikipedia <ref>{{Cite pmid|23656993}}</ref> Disconnection of the Ascending Arousal System in Traumatic Coma #MMPMID23656993 Edlow BL; Haynes RL; Takahashi E; Klein JP; Cummings P; Benner T; Greer DM; Greenberg SM; Wu O; Kinney HC; Folkerth RD J Neuropathol Exp Neurol 2013[Jun]; 72 (6): 505-23 PMID23656993show ga Traumatic coma is associated with disruption of axonal pathways throughout the brain but the specific pathways involved in humans are incompletely understood. In this study, we used high angular resolution diffusion imaging (HARDI) to map the connectivity of axonal pathways that mediate the 2 critical components of consciousness ? arousal and awareness ? in the postmortem brain of a 62-year-old woman with acute traumatic coma and in 2 control brains. HARDI tractography guided tissue sampling in the neuropathological analysis. HARDI tractography demonstrated complete disruption of white matter pathways connecting brainstem arousal nuclei to the basal forebrain and thalamic intralaminar and reticular nuclei. In contrast, hemispheric arousal pathways connecting the thalamus and basal forebrain to the cerebral cortex were only partially disrupted, as were the cortical ?awareness pathways.? Neuropathologic examination, which utilized ?-amyloid precursor protein and fractin immunomarkers, revealed axonal injury in the white matter of the brainstem and cerebral hemispheres that corresponded to sites of HARDI tract disruption. Axonal injury was also present within the grey matter of the hypothalamus, thalamus, basal forebrain, and cerebral cortex. We propose that traumatic coma may be a subcortical disconnection syndrome related to the disconnection of specific brainstem arousal nuclei from the thalamus and basal forebrain. äDisconnection of the Ascending Arousal System in Traumatic Coma (epmc).pdf DeepDyve Pubget Overpricing