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10.1107/S1744309113018551

http://scihub22266oqcxt.onion/10.1107/S1744309113018551
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C3758163!3758163!23989163
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suck abstract from ncbi


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pmid23989163      Acta+Crystallogr+Sect+F+Struct+Biol+Cryst+Commun 2013 ; 69 (Pt 9): 1060-5
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  • Identifying ligand-binding hot spots in proteins using brominated fragments #MMPMID23989163
  • Grøftehauge MK; Therkelsen MØ; Taaning R; Skrydstrup T; Morth JP; Nissen P
  • Acta Crystallogr Sect F Struct Biol Cryst Commun 2013[Sep]; 69 (Pt 9): 1060-5 PMID23989163show ga
  • X-ray crystallographic screening can provide both leads for high-affinity small-molecule development and information about potential substrate sites. In this study, in work on the well-studied protein T. thermophilus EF-Tu, brominated fragments were used for easy identification in anomalous maps.
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