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10.1016/j.beem.2013.03.002 http://scihub22266oqcxt.onion/10.1016/j.beem.2013.03.002 C3713412!3713412!23856269     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Best+Pract+Res+Clin+Endocrinol+Metab 2013 ; 27 (3): 415-27 Nephropedia Template TP {{tp|p=23856269|t=2013. Role of the calcium-sensing receptor in calcium regulation of epidermal differentiation and function |pdf=|usr=}}{{23856269}} gab.com Text Role of the calcium-sensing receptor in calcium regulation of epidermal differentiation and function JO: Best Pract Res Clin Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=23856269 #FOAvip The epidermis is a stratified squamous epithelium composed of proliferating basal and differentiated suprabasal keratinocytes. It serves as the body?s major physical and chemical barrier against infection and harsh environmental insults, as well as preventing excess water loss from the body into the atmosphere. Calcium is a key regulator of the proliferation and differentiation in keratinocytes. Elevated extracellular Ca2+ concentration ([Ca2+]o) raises the levels of intracellular free calcium ([Ca2+]i), promotes cell-cell adhesion, and activates differentiation-related genes. Keratinocytes deficient in the calcium-sensing receptor fail to respond to [Ca2+]o stimulation and to differentiate, indicating a role for the calcium-sensing receptor in transducing the [Ca2+]o signal during differentiation. The concepts derived from in vitro gene knockdown experiments have been evaluated and confirmed in three mouse models in vivo. Twit Text FOAVip Role of the calcium-sensing receptor in calcium regulation of epidermal differentiation and function ????Best Pract Res Clin Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=23856269 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23856269 #FOAvip English Wikipedia <ref>{{Cite pmid|23856269}}</ref> Role of the calcium-sensing receptor in calcium regulation of epidermal differentiation and function #MMPMID23856269 Tu CL; Bikle DD Best Pract Res Clin Endocrinol Metab 2013[Jun]; 27 (3): 415-27 PMID23856269show ga The epidermis is a stratified squamous epithelium composed of proliferating basal and differentiated suprabasal keratinocytes. It serves as the body?s major physical and chemical barrier against infection and harsh environmental insults, as well as preventing excess water loss from the body into the atmosphere. Calcium is a key regulator of the proliferation and differentiation in keratinocytes. Elevated extracellular Ca2+ concentration ([Ca2+]o) raises the levels of intracellular free calcium ([Ca2+]i), promotes cell-cell adhesion, and activates differentiation-related genes. Keratinocytes deficient in the calcium-sensing receptor fail to respond to [Ca2+]o stimulation and to differentiate, indicating a role for the calcium-sensing receptor in transducing the [Ca2+]o signal during differentiation. The concepts derived from in vitro gene knockdown experiments have been evaluated and confirmed in three mouse models in vivo. äRole of the calcium-sensing receptor in calcium regulation of epiderma(epmc).pdf DeepDyve Pubget Overpricing