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10.1074/jbc.M113.471060 http://scihub22266oqcxt.onion/10.1074/jbc.M113.471060 C3696659!3696659!23671278     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2013 ; 288 (26): 18834-41 Nephropedia Template TP {{tp|p=23671278|t=2013. CD163 Binding to Haptoglobin-Hemoglobin Complexes Involves a Dual-point Electrostatic Receptor-Ligand Pairing* |pdf=|usr=}}{{23671278}} gab.com Text CD163 Binding to Haptoglobin-Hemoglobin Complexes Involves a Dual-point Electrostatic Receptor-Ligand Pairing* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=23671278 #FOAvip Background: CD163 mediates endocytosis of haptoglobin-hemoglobin complexes formed upon intravascular hemolysis.Results: Acidic CD163 residues and basic haptoglobin residues mediate receptor-ligand binding in humans.Conclusion: A two-point electrostatic pairing between Ca2+-coordinated acidic clusters in receptors and basic ligand residues explains high-affinity CD163-(haptoglobin-hemoglobin) binding.Significance: The data add further evidence that Ca2+-dependent two-point electrostatic pairing is a common mechanism for coupling ligands to endocytic receptors. Twit Text FOAVip CD163 Binding to Haptoglobin-Hemoglobin Complexes Involves a Dual-point Electrostatic Receptor-Ligand Pairing* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=23671278 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23671278 #FOAvip English Wikipedia <ref>{{Cite pmid|23671278}}</ref> CD163 Binding to Haptoglobin-Hemoglobin Complexes Involves a Dual-point Electrostatic Receptor-Ligand Pairing* #MMPMID23671278 Nielsen MJ; Andersen CBF; Moestrup SK J Biol Chem 2013[Jun]; 288 (26): 18834-41 PMID23671278show ga Background: CD163 mediates endocytosis of haptoglobin-hemoglobin complexes formed upon intravascular hemolysis.Results: Acidic CD163 residues and basic haptoglobin residues mediate receptor-ligand binding in humans.Conclusion: A two-point electrostatic pairing between Ca2+-coordinated acidic clusters in receptors and basic ligand residues explains high-affinity CD163-(haptoglobin-hemoglobin) binding.Significance: The data add further evidence that Ca2+-dependent two-point electrostatic pairing is a common mechanism for coupling ligands to endocytic receptors. äCD163 Binding to Haptoglobin-Hemoglobin Complexes Involves a Dual-poin(epmc).pdf DeepDyve Pubget Overpricing