Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Assist+Reprod+Genet 2013 ; 30 (6): 835-41 Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Effect of micro-vibration culture system on embryo development #MMPMID23657828
Hur YS; Park JH; Ryu EK; Park SJ; Lee JH; Lee SH; Yoon J; Yoon SH; Hur CY; Lee WD; Lim JH
J Assist Reprod Genet 2013[Jun]; 30 (6): 835-41 PMID23657828show ga
Purpose: Micro-vibration culture system was examined to determine the effects on mouse and human embryo development and possible improvement of clinical outcomes in poor responders. Materials and methods: The embryonic development rates and cell numbers of blastocysts were compared between a static culture group (n?=?178) and a micro-vibration culture group (n?=?181) in mice. The embryonic development rates and clinical results were compared between a static culture group (n?=?159 cycles) and a micro-vibration culture group (n?=?166 cycles) in poor responders. A micro-vibrator was set at a frequency of 42 Hz, 5 s/60 min duration for mouse and human embryo development. Results: The embryonic development rate was significantly improved in the micro-vibration culture group in mice (p?0.05). The cell numbers of mouse blastocysts were significantly higher in the micro-vibration group than in the static culture group (p?0.05). In the poor responders, the rate of high grade embryos was not significantly improved in the micro-vibration culture group on day 3. However, the optimal embryonic development rate on day 5 was improved in the micro-vibration group, and the total pregnancy rate and implantation rate were significantly higher in the micro-vibration group than in the static culture group (p?0.05). Conclusions: Micro-vibration culture methods have a beneficial effect on embryonic development in mouse embryos. In poor responders, the embryo development rate was improved to a limited extent under the micro-vibration culture conditions, but the clinical results were significantly improved.