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10.1074/jbc.M112.436584

http://scihub22266oqcxt.onion/10.1074/jbc.M112.436584
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C3689958!3689958!23640897
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suck abstract from ncbi


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pmid23640897      J+Biol+Chem 2013 ; 288 (25): 18146-61
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  • Lacritin Rescues Stressed Epithelia via Rapid Forkhead Box O3 (FOXO3)-associated Autophagy That Restores Metabolism* #MMPMID23640897
  • Wang N; Zimmerman K; Raab RW; McKown RL; Hutnik CML; Talla V; Tyler MF; Lee JK; Laurie GW
  • J Biol Chem 2013[Jun]; 288 (25): 18146-61 PMID23640897show ga
  • Background: Homeostatic regulation of epithelia influences disease acquisition and aging.Results: Prosecretory mitogen lacritin stimulates FOXO3-ATG101 and FOXO1-ATG7 autophagic coupling and restores metabolic homeostasis.Conclusion: Lacritin is a homeostatic regulator.Significance: Exogenous lacritin restores prohomeostatic activity to tears from dry eye individuals.
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