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10.1063/1.4809513

http://scihub22266oqcxt.onion/10.1063/1.4809513
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C3689753!3689753!23825806
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suck abstract from ncbi


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pmid23825806      Appl+Phys+Lett 2013 ; 102 (22): ä
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  • Enhanced fluorescence emission using a photonic crystal coupled to an optical cavity #MMPMID23825806
  • Pokhriyal A; Lu M; Chaudhery V; George S; Cunningham BT
  • Appl Phys Lett 2013[Jun]; 102 (22): ä PMID23825806show ga
  • All fluorescent assays would benefit from greater signal-to-noise ratios (SNRs), which enable detection of disease biomarkers at lower concentrations for earlier disease diagnosis and detection of genes that are expressed at the lowest levels. Here, we report an approach to enhance fluorescence in which surface adsorbed fluorophore-tagged biomolecules are excited on a photonic crystal surface that is coupled to an underlying Fabry-Perot type cavity through a gold mirror reflector beneath the photonic crystal. This approach leads to 6× increase in signal-to-noise ratio of a dye labeled polypeptide compared to ordinary photonic crystal enhanced fluorescence.
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