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10.1182/blood-2012-10-464198 http://scihub22266oqcxt.onion/10.1182/blood-2012-10-464198 C3689252!3689252 !23547053     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\23547053 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Blood 2013 ; 121 (25 ): 5098-103 Nephropedia Template TP {{tp|p=23547053 |t=2013. Incidence, risk factors, and outcomes of sclerosis in patients with chronic graft-versus-host disease |pdf=|usr=}}{{23547053 }} gab.com Text Incidence, risk factors, and outcomes of sclerosis in patients with chronic graft-versus-host disease JO: Blood http://www.kidney.de/pget.php?&tw=1&pmid=23547053 #FOAvip Sclerotic chronic graft-versus-host disease (GVHD) can result in disability after allogeneic hematopoietic cell transplantation. We assessed the incidence and risk factors of sclerosis and its association with transplant outcomes among 977 consecutive patients treated with systemic immunosuppression for chronic GVHD. Sclerosis was defined when cutaneous sclerosis, fasciitis, or joint contracture was first documented in the medical record. Seventy (7%) patients presented with sclerosis at the time of initial systemic treatment for chronic GVHD, and the cumulative incidence of sclerosis increased to 20% at 3 years. Factors associated with an increased risk of sclerosis included the use of a mobilized blood cell graft and a conditioning regimen with > 450 cGy total body irradiation. Factors associated with a decreased risk of sclerosis included the use of an HLA-mismatched donor and a major ABO-mismatched donor. Development of sclerosis was associated with longer time to withdrawal of immunosuppressive treatment but not with risks of overall mortality, nonrelapse mortality, or recurrent malignancy. We found a substantial incidence of sclerosis in patients with chronic GVHD. Development of sclerosis can cause disability but does not affect mortality or recurrent malignancy in patients with chronic GVHD. Twit Text FOAVip Incidence, risk factors, and outcomes of sclerosis in patients with chronic graft-versus-host disease ????Blood http://www.kidney.de/pget.php?&tw=1&pmid=23547053 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23547053 #FOAvip English Wikipedia <ref>{{Cite pmid|23547053 }}</ref> Incidence, risk factors, and outcomes of sclerosis in patients with chronic graft-versus-host disease #MMPMID23547053 Inamoto Y ; Storer BE ; Petersdorf EW ; Nelson JL ; Lee SJ ; Carpenter PA ; Sandmaier BM ; Hansen JA ; Martin PJ ; Flowers ME Blood 2013[Jun]; 121 (25 ): 5098-103 PMID23547053 show ga Sclerotic chronic graft-versus-host disease (GVHD) can result in disability after allogeneic hematopoietic cell transplantation. We assessed the incidence and risk factors of sclerosis and its association with transplant outcomes among 977 consecutive patients treated with systemic immunosuppression for chronic GVHD. Sclerosis was defined when cutaneous sclerosis, fasciitis, or joint contracture was first documented in the medical record. Seventy (7%) patients presented with sclerosis at the time of initial systemic treatment for chronic GVHD, and the cumulative incidence of sclerosis increased to 20% at 3 years. Factors associated with an increased risk of sclerosis included the use of a mobilized blood cell graft and a conditioning regimen with > 450 cGy total body irradiation. Factors associated with a decreased risk of sclerosis included the use of an HLA-mismatched donor and a major ABO-mismatched donor. Development of sclerosis was associated with longer time to withdrawal of immunosuppressive treatment but not with risks of overall mortality, nonrelapse mortality, or recurrent malignancy. We found a substantial incidence of sclerosis in patients with chronic GVHD. Development of sclerosis can cause disability but does not affect mortality or recurrent malignancy in patients with chronic GVHD. |Adolescent [MESH] |Adult [MESH] |Aged [MESH] |Child [MESH] |Child, Preschool [MESH] |Chronic Disease [MESH] |Female [MESH] |Graft vs Host Disease/*pathology [MESH] |HLA Antigens [MESH] |Hematopoietic Stem Cell Transplantation/adverse effects [MESH] |Humans [MESH] |Immunosuppression Therapy/adverse effects [MESH] |Incidence [MESH] |Infant [MESH] |Infant, Newborn [MESH] |Male [MESH] |Middle Aged [MESH] |Risk Factors [MESH] |Sclerosis/epidemiology [MESH] |Transplantation Conditioning/adverse effects [MESH]Incidence, risk factors, and outcomes of sclerosis in patients with ch(epmc).pdf DeepDyve Pubget Overpricing