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10.1101/cshperspect.a013326 http://scihub22266oqcxt.onion/10.1101/cshperspect.a013326 C3683901!3683901!23545423     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cold+Spring+Harb+Perspect+Biol 2013 ; 5 (4): ä Nephropedia Template TP {{tp|p=23545423|t=2013. Sphingolipid Homeostasis in the Endoplasmic Reticulum and Beyond |pdf=|usr=}}{{23545423}} gab.com Text Sphingolipid Homeostasis in the Endoplasmic Reticulum and Beyond JO: Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=23545423 #FOAvip Sphingolipids are a diverse group of lipids that have essential cellular roles as structural components of membranes and as potent signaling molecules. In recent years, a detailed picture has emerged of the basic biochemistry of sphingolipids?from their initial synthesis in the endoplasmic reticulum (ER), to their elaboration into complex glycosphingolipids, to their turnover and degradation. However, our understanding of how sphingolipid metabolism is regulated in response to metabolic demand and physiologic cues remains incomplete. Here I discuss new insights into the mechanisms that ensure sphingolipid homeostasis, with an emphasis on the ER as a critical regulatory site in sphingolipid metabolism. In particular, Orm family proteins have recently emerged as key ER-localized mediators of sphingolipid homeostasis. A detailed understanding of how cells sense and control sphingolipid production promises to provide key insights into membrane function in health and disease. Twit Text FOAVip Sphingolipid Homeostasis in the Endoplasmic Reticulum and Beyond ????Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=23545423 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23545423 #FOAvip English Wikipedia <ref>{{Cite pmid|23545423}}</ref> Sphingolipid Homeostasis in the Endoplasmic Reticulum and Beyond #MMPMID23545423 Breslow DK Cold Spring Harb Perspect Biol 2013[Apr]; 5 (4): ä PMID23545423show ga Sphingolipids are a diverse group of lipids that have essential cellular roles as structural components of membranes and as potent signaling molecules. In recent years, a detailed picture has emerged of the basic biochemistry of sphingolipids?from their initial synthesis in the endoplasmic reticulum (ER), to their elaboration into complex glycosphingolipids, to their turnover and degradation. However, our understanding of how sphingolipid metabolism is regulated in response to metabolic demand and physiologic cues remains incomplete. Here I discuss new insights into the mechanisms that ensure sphingolipid homeostasis, with an emphasis on the ER as a critical regulatory site in sphingolipid metabolism. In particular, Orm family proteins have recently emerged as key ER-localized mediators of sphingolipid homeostasis. A detailed understanding of how cells sense and control sphingolipid production promises to provide key insights into membrane function in health and disease. äSphingolipid Homeostasis in the Endoplasmic Reticulum and Beyond (epmc).pdf DeepDyve Pubget Overpricing