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Deprecated: Implicit conversion from float 284.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Biol+Chem 2013 ; 288 (23): 16680-9 Nephropedia Template TP
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IOP1 Protein Is an External Component of the Human Cytosolic Iron-Sulfur Cluster Assembly (CIA) Machinery and Functions in the MMS19 Protein-dependent CIA Pathway* #MMPMID23585563
Seki M; Takeda Y; Iwai K; Tanaka K
J Biol Chem 2013[Jun]; 288 (23): 16680-9 PMID23585563show ga
Background: The CIA machinery in human cells is unclear.Results: MMS19 formed a complex with MIP18, CIAO1, and IOP1, but IOP1 behaved differently from the other components.Conclusion: The CIA complex consists of a core MMS19-MIP18-CIAO1 complex, and IOP1 is an external component of the CIA machinery.Significance: This study increases the understanding of the composition of the CIA machinery in human cells and the interactions between the components.