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10.1007/s11912-013-0315-7 http://scihub22266oqcxt.onion/10.1007/s11912-013-0315-7 C3674487!3674487 !23568600     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\23568600 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Oncol+Rep 2013 ; 15 (3 ): 207-16 Nephropedia Template TP {{tp|p=23568600 |t=2013. The role of vascular endothelial growth factor in the pathogenesis, diagnosis and treatment of malignant pleural effusion |pdf=|usr=}}{{23568600 }} gab.com Text The role of vascular endothelial growth factor in the pathogenesis, diagnosis and treatment of malignant pleural effusion JO: Curr Oncol Rep http://www.kidney.de/pget.php?&tw=1&pmid=23568600 #FOAvip Malignant pleural effusions (MPEs) are a significant source of cancer-related morbidity. Over 150,000 patients in the United States suffer from breathlessness and diminished quality of life due to MPE each year. Current management strategies are of mostly palliative value and focus on symptom control; they do not address the pathobiology of the effusion, nor do they improve survival. Further elucidation of the pathophysiological mechanisms, coupled with the development of novel treatments such as intrapleural chemotherapeutics targeting this process, has the potential to greatly improve the efficacy of our current management options. Vascular endothelial growth factor-A (VEGF-A) has been implicated as a critical cytokine in the formation of malignant pleural effusions. Elevated levels of VEGF produced by tumor cells, mesothelial cells, and infiltrating immune cells result in increased vascular permeability, cancer cell transmigration, and angiogenesis. Therefore antiangiogenic therapies such as Bevacizumab, a monoclonal antibody targeting VEGF-A, may have a potential role in the management of malignant pleural effusions. Herein we review the pathogenesis and potential treatment strategies of malignant pleural effusions, with a focus on angiogenesis and antiangiogenic therapeutics. Twit Text FOAVip The role of vascular endothelial growth factor in the pathogenesis, diagnosis and treatment of malignant pleural effusion ????Curr Oncol Rep http://www.kidney.de/pget.php?&tw=1&pmid=23568600 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23568600 #FOAvip English Wikipedia <ref>{{Cite pmid|23568600 }}</ref> The role of vascular endothelial growth factor in the pathogenesis, diagnosis and treatment of malignant pleural effusion #MMPMID23568600 Bradshaw M ; Mansfield A ; Peikert T Curr Oncol Rep 2013[Jun]; 15 (3 ): 207-16 PMID23568600 show ga Malignant pleural effusions (MPEs) are a significant source of cancer-related morbidity. Over 150,000 patients in the United States suffer from breathlessness and diminished quality of life due to MPE each year. Current management strategies are of mostly palliative value and focus on symptom control; they do not address the pathobiology of the effusion, nor do they improve survival. Further elucidation of the pathophysiological mechanisms, coupled with the development of novel treatments such as intrapleural chemotherapeutics targeting this process, has the potential to greatly improve the efficacy of our current management options. Vascular endothelial growth factor-A (VEGF-A) has been implicated as a critical cytokine in the formation of malignant pleural effusions. Elevated levels of VEGF produced by tumor cells, mesothelial cells, and infiltrating immune cells result in increased vascular permeability, cancer cell transmigration, and angiogenesis. Therefore antiangiogenic therapies such as Bevacizumab, a monoclonal antibody targeting VEGF-A, may have a potential role in the management of malignant pleural effusions. Herein we review the pathogenesis and potential treatment strategies of malignant pleural effusions, with a focus on angiogenesis and antiangiogenic therapeutics. |Angiogenesis Inhibitors/*therapeutic use [MESH] |Antibodies, Monoclonal, Humanized/*therapeutic use [MESH] |Bevacizumab [MESH] |Biomarkers, Tumor/metabolism [MESH] |Catheters, Indwelling [MESH] |Female [MESH] |Humans [MESH] |Lung Neoplasms/*drug therapy/metabolism/pathology [MESH] |Male [MESH] |Pleural Effusion, Malignant/*drug therapy/metabolism/pathology [MESH] |Quality of Life [MESH] |Time Factors [MESH] |Treatment Outcome [MESH]The role of vascular endothelial growth factor in the pathogenesis, di(epmc).pdf DeepDyve Pubget Overpricing