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10.1021/ac401058v http://scihub22266oqcxt.onion/10.1021/ac401058v C3674208!3674208!23635325     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Anal+Chem 2013 ; 85 (11): 5304-10 Nephropedia Template TP {{tp|p=23635325|t=2013. Multiplexed Electrochemical Protein Detection and Translation to Personalized Cancer Diagnostics |pdf=|usr=}}{{23635325}} gab.com Text Multiplexed Electrochemical Protein Detection and Translation to Personalized Cancer Diagnostics JO: Anal Chem http://www.kidney.de/pget.php?&tw=1&pmid=23635325 #FOAvip Measuring diagnostic panels of multiple proteins promises a new, personalized approach to early detection and therapy of diseases like cancer. Levels of biomarker proteins in patient serum can provide a continually updated record of disease status. Research in electrochemical detection of proteins has produced exquisitely sensitive approaches. Most utilize ELISA-like sandwich immunoassays incorporating various aspects of nanotechnology. Several of these ultrasensitive methodologies have been extended to microfluidic multiplexed protein detection, but engineered solutions are needed to measure more proteins in a single device from a small patient sample such as a drop of blood or tissue lysate. To achieve clinical or point-of-care (POC) use, simplicity and low cost are essential. In multiplexed microfluidic immunoassays, required reagent additions and washing steps pose a significant problem calling for creative engineering. A grand challenge is to develop a general cancer screening device to accurately measure 50?100 proteins in a simple, cost effective fashion. This will require creative solutions to simplified reagent addition and multiplexing. Twit Text FOAVip Multiplexed Electrochemical Protein Detection and Translation to Personalized Cancer Diagnostics ????Anal Chem http://www.kidney.de/pget.php?&tw=1&pmid=23635325 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23635325 #FOAvip English Wikipedia <ref>{{Cite pmid|23635325}}</ref> Multiplexed Electrochemical Protein Detection and Translation to Personalized Cancer Diagnostics #MMPMID23635325 Rusling JF Anal Chem 2013[Jun]; 85 (11): 5304-10 PMID23635325show ga Measuring diagnostic panels of multiple proteins promises a new, personalized approach to early detection and therapy of diseases like cancer. Levels of biomarker proteins in patient serum can provide a continually updated record of disease status. Research in electrochemical detection of proteins has produced exquisitely sensitive approaches. Most utilize ELISA-like sandwich immunoassays incorporating various aspects of nanotechnology. Several of these ultrasensitive methodologies have been extended to microfluidic multiplexed protein detection, but engineered solutions are needed to measure more proteins in a single device from a small patient sample such as a drop of blood or tissue lysate. To achieve clinical or point-of-care (POC) use, simplicity and low cost are essential. In multiplexed microfluidic immunoassays, required reagent additions and washing steps pose a significant problem calling for creative engineering. A grand challenge is to develop a general cancer screening device to accurately measure 50?100 proteins in a simple, cost effective fashion. This will require creative solutions to simplified reagent addition and multiplexing. äMultiplexed Electrochemical Protein Detection and Translation to Perso(epmc).pdf DeepDyve Pubget Overpricing