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10.1016/j.ahj.2013.03.001 http://scihub22266oqcxt.onion/10.1016/j.ahj.2013.03.001 C3664840!3664840 !23708168     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\23708168 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Am+Heart+J 2013 ; 165 (6 ): 964-971.e1 Nephropedia Template TP {{tp|p=23708168 |t=2013. Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease |pdf=|usr=}}{{23708168 }} gab.com Text Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease JO: Am Heart J http://www.kidney.de/pget.php?&tw=1&pmid=23708168 #FOAvip BACKGROUND: Prior trials suggest it is safe to defer transfusion at hemoglobin levels above 7 to 8 g/dL in most patients. Patients with acute coronary syndrome may benefit from higher hemoglobin levels. METHODS: We performed a pilot trial in 110 patients with acute coronary syndrome or stable angina undergoing cardiac catheterization and a hemoglobin <10 g/dL. Patients in the liberal transfusion strategy received one or more units of blood to raise the hemoglobin level ?10 g/dL. Patients in the restrictive transfusion strategy were permitted to receive blood for symptoms from anemia or for a hemoglobin <8 g/dL. The predefined primary outcome was the composite of death, myocardial infarction, or unscheduled revascularization 30 days post randomization. RESULTS: Baseline characteristics were similar between groups except age (liberal, 67.3; restrictive, 74.3). The mean number of units transfused was 1.6 in the liberal group and 0.6 in the restrictive group. The primary outcome occurred in 6 patients (10.9%) in the liberal group and 14 (25.5%) in the restrictive group (risk difference = 15.0%; 95% confidence interval of difference 0.7% to 29.3%; P = .054 and adjusted for age P = .076). Death at 30 days was less frequent in liberal group (n = 1, 1.8%) compared to restrictive group (n = 7, 13.0%; P = .032). CONCLUSIONS: The liberal transfusion strategy was associated with a trend for fewer major cardiac events and deaths than a more restrictive strategy. These results support the feasibility of and the need for a definitive trial. Twit Text FOAVip Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease ????Am Heart J http://www.kidney.de/pget.php?&tw=1&pmid=23708168 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23708168 #FOAvip English Wikipedia <ref>{{Cite pmid|23708168 }}</ref> Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease #MMPMID23708168 Carson JL ; Brooks MM ; Abbott JD ; Chaitman B ; Kelsey SF ; Triulzi DJ ; Srinivas V ; Menegus MA ; Marroquin OC ; Rao SV ; Noveck H ; Passano E ; Hardison RM ; Smitherman T ; Vagaonescu T ; Wimmer NJ ; Williams DO Am Heart J 2013[Jun]; 165 (6 ): 964-971.e1 PMID23708168 show ga BACKGROUND: Prior trials suggest it is safe to defer transfusion at hemoglobin levels above 7 to 8 g/dL in most patients. Patients with acute coronary syndrome may benefit from higher hemoglobin levels. METHODS: We performed a pilot trial in 110 patients with acute coronary syndrome or stable angina undergoing cardiac catheterization and a hemoglobin <10 g/dL. Patients in the liberal transfusion strategy received one or more units of blood to raise the hemoglobin level ?10 g/dL. Patients in the restrictive transfusion strategy were permitted to receive blood for symptoms from anemia or for a hemoglobin <8 g/dL. The predefined primary outcome was the composite of death, myocardial infarction, or unscheduled revascularization 30 days post randomization. RESULTS: Baseline characteristics were similar between groups except age (liberal, 67.3; restrictive, 74.3). The mean number of units transfused was 1.6 in the liberal group and 0.6 in the restrictive group. The primary outcome occurred in 6 patients (10.9%) in the liberal group and 14 (25.5%) in the restrictive group (risk difference = 15.0%; 95% confidence interval of difference 0.7% to 29.3%; P = .054 and adjusted for age P = .076). Death at 30 days was less frequent in liberal group (n = 1, 1.8%) compared to restrictive group (n = 7, 13.0%; P = .032). CONCLUSIONS: The liberal transfusion strategy was associated with a trend for fewer major cardiac events and deaths than a more restrictive strategy. These results support the feasibility of and the need for a definitive trial. |*Decision Making [MESH] |Blood Transfusion/*methods [MESH] |Cardiac Catheterization [MESH] |Coronary Artery Disease/blood/diagnosis/*therapy [MESH] |Death, Sudden, Cardiac/epidemiology/prevention & control [MESH] |Electrocardiography [MESH] |Follow-Up Studies [MESH] |Hemoglobins/*metabolism [MESH] |Humans [MESH] |Incidence [MESH] |Pilot Projects [MESH] |Prognosis [MESH] |Retrospective Studies [MESH] |Survival Rate/trends [MESH]Liberal versus restrictive transfusion thresholds for patients with sy(epmc).pdf DeepDyve Pubget Overpricing