Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1128/JVI.05341-11 http://scihub22266oqcxt.onion/10.1128/JVI.05341-11 C3196408!3196408!21752902     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Virol 2011 ; 85 (19): 10109-16 Nephropedia Template TP {{tp|p=21752902|t=2011. Type 1 Responses of Human V?9V?2 T Cells to Influenza A Viruses? |pdf=|usr=}}{{21752902}} gab.com Text Type 1 Responses of Human V 9V 2 T Cells to Influenza A Viruses JO: J Virol http://www.kidney.de/pget.php?&tw=1&pmid=21752902 #FOAvip ?? T cells are essential constituents of antimicrobial and antitumor defenses. We have recently reported that phosphoantigen isopentenyl pyrophosphate (IPP)-expanded human V?9V?2 T cells participated in anti-influenza virus immunity by efficiently killing both human and avian influenza virus-infected monocyte-derived macrophages (MDMs) in vitro. However, little is known about the noncytolytic responses and trafficking program of ?? T cells to influenza virus. In this study, we found that V?9V?2 T cells expressed both type 1 cytokines and chemokine receptors during influenza virus infection, and IPP-expanded cells had a higher capacity to produce gamma interferon (IFN-?). Besides their potent cytolytic activity against pandemic H1N1 virus-infected cells, IPP-activated ?? T cells also had noncytolytic inhibitory effects on seasonal and pandemic H1N1 viruses via IFN-? but had no such effects on avian H5N1 or H9N2 virus. Avian H5N1 and H9N2 viruses induced significantly higher CCL3, CCL4, and CCL5 production in V?9V?2 T cells than human seasonal H1N1 virus. CCR5 mediated the migration of V?9V?2 T cells toward influenza virus-infected cells. Our findings suggest a novel therapeutic strategy of using phosphoantigens to boost the antiviral activities of human V?9V?2 T cells against influenza virus infection. Twit Text FOAVip Type 1 Responses of Human V 9V 2 T Cells to Influenza A Viruses ????J Virol http://www.kidney.de/pget.php?&tw=1&pmid=21752902 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21752902 #FOAvip English Wikipedia <ref>{{Cite pmid|21752902}}</ref> Type 1 Responses of Human V?9V?2 T Cells to Influenza A Viruses? #MMPMID21752902 Qin G; Liu Y; Zheng J; Ng IHY; Xiang Z; Lam KT; Mao H; Li H; Peiris JSM; Lau YL; Tu W J Virol 2011[Oct]; 85 (19): 10109-16 PMID21752902show ga ?? T cells are essential constituents of antimicrobial and antitumor defenses. We have recently reported that phosphoantigen isopentenyl pyrophosphate (IPP)-expanded human V?9V?2 T cells participated in anti-influenza virus immunity by efficiently killing both human and avian influenza virus-infected monocyte-derived macrophages (MDMs) in vitro. However, little is known about the noncytolytic responses and trafficking program of ?? T cells to influenza virus. In this study, we found that V?9V?2 T cells expressed both type 1 cytokines and chemokine receptors during influenza virus infection, and IPP-expanded cells had a higher capacity to produce gamma interferon (IFN-?). Besides their potent cytolytic activity against pandemic H1N1 virus-infected cells, IPP-activated ?? T cells also had noncytolytic inhibitory effects on seasonal and pandemic H1N1 viruses via IFN-? but had no such effects on avian H5N1 or H9N2 virus. Avian H5N1 and H9N2 viruses induced significantly higher CCL3, CCL4, and CCL5 production in V?9V?2 T cells than human seasonal H1N1 virus. CCR5 mediated the migration of V?9V?2 T cells toward influenza virus-infected cells. Our findings suggest a novel therapeutic strategy of using phosphoantigens to boost the antiviral activities of human V?9V?2 T cells against influenza virus infection. äType 1 Responses of Human V?9V?2 T Cells to Influenza A Viruses? (epmc).pdf DeepDyve Pubget Overpricing