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10.1371/journal.pone.0020495 http://scihub22266oqcxt.onion/10.1371/journal.pone.0020495 C3105060!3105060 !21655265     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\21655265 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       PLoS+One 2011 ; 6 (5 ): e20495 Nephropedia Template TP {{tp|p=21655265 |t=2011. Immunolocalization of influenza A virus and markers of inflammation in the human Parkinson s disease brain |pdf=|usr=}}{{21655265 }} gab.com Text Immunolocalization of influenza A virus and markers of inflammation in the human Parkinson s disease brain JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=21655265 #FOAvip Although much is known regarding the molecular mechanisms leading to neuronal cell loss in Parkinson's disease (PD), the initiating event has not been identified. Prevailing theories including a chemical insult or infectious agent have been postulated as possible triggers, leading to neuroinflammation. We present immunohistochemical data indicating the presence of influenza A virus within the substantia nigra pars compacta (SNpc) from postmortem PD brain sections. Influenza A virus labeling was identified within neuromelanin granules as well as on tissue macrophages in the SNpc. Further supporting a role for neuroinflammation in PD was the identification of T-lymphocytes that colocalized with an antibody to caspase-cleaved Beclin-1 within the SNpc. The presence of influenza A virus together with macrophages and T-lymphocytes may contribute to the neuroinflammation associated with this disease. Twit Text FOAVip Immunolocalization of influenza A virus and markers of inflammation in the human Parkinson s disease brain ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=21655265 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21655265 #FOAvip English Wikipedia <ref>{{Cite pmid|21655265 }}</ref> Immunolocalization of influenza A virus and markers of inflammation in the human Parkinson s disease brain #MMPMID21655265 Rohn TT ; Catlin LW PLoS One 2011[]; 6 (5 ): e20495 PMID21655265 show ga Although much is known regarding the molecular mechanisms leading to neuronal cell loss in Parkinson's disease (PD), the initiating event has not been identified. Prevailing theories including a chemical insult or infectious agent have been postulated as possible triggers, leading to neuroinflammation. We present immunohistochemical data indicating the presence of influenza A virus within the substantia nigra pars compacta (SNpc) from postmortem PD brain sections. Influenza A virus labeling was identified within neuromelanin granules as well as on tissue macrophages in the SNpc. Further supporting a role for neuroinflammation in PD was the identification of T-lymphocytes that colocalized with an antibody to caspase-cleaved Beclin-1 within the SNpc. The presence of influenza A virus together with macrophages and T-lymphocytes may contribute to the neuroinflammation associated with this disease. |Apoptosis Regulatory Proteins/metabolism [MESH] |Beclin-1 [MESH] |Brain/*metabolism/*virology [MESH] |Humans [MESH] |Immunohistochemistry [MESH] |In Situ Nick-End Labeling [MESH] |In Vitro Techniques [MESH] |Inflammation/*metabolism [MESH] |Influenza A virus/*isolation & purification [MESH] |Melanins/metabolism [MESH] |Membrane Proteins/metabolism [MESH] |Microscopy, Fluorescence [MESH] |Parkinson Disease/*metabolism/*virology [MESH] |Substantia Nigra/metabolism/virology [MESH]Immunolocalization of influenza A virus and markers of inflammation in(epmc).pdf DeepDyve Pubget Overpricing