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2004 ; 132
(5
): 797-803
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Factors associated with transmission of severe acute respiratory syndrome among
health-care workers in Singapore
#MMPMID15473141
Teleman MD
; Boudville IC
; Heng BH
; Zhu D
; Leo YS
Epidemiol Infect
2004[Oct]; 132
(5
): 797-803
PMID15473141
show ga
Between 1 and 22 March 2003, a nosocomial outbreak of Severe Acute Respiratory
Syndrome (SARS) occurred at the Communicable Disease Centre in Tan Tock Seng
Hospital, Singapore, the national treatment and isolation facility for patients
with SARS. A case-control study with 36 cases and 50 controls was conducted of
factors associated with the transmission of SARS within the hospital. In
univariate analysis, contact with respiratory secretions elevated the odds ratio
to 6.9 (95 % CI 1.4-34.6, P= 0.02). Protection was conferred by hand washing (OR
0.06, 95% CI 0.007-0.5, P=0.03) and wearing of N95 masks (OR 0.1, 95% CI
0.03-0.4, P=0.001). Use of gloves and gowns had no effect. Multivariate analysis
confirmed the strong role of contact with respiratory secretions (adjusted OR
21.8, 95 % CI 1.7 274.8, P=0.017). Both hand washing (adjusted OR 0.07, 95 % CI
0.008-0.66, P=0.02) and wearing of N95 masks (adjusted OR 0.1, 95% CI 0.02-0.86,
P=0.04) remained strongly protective but gowns and gloves had no effect.